- Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer
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Kandhari K, Paudel S, Raina K, Agarwal C, Kant R, Wempe MF, Bryant CO, Agarwal R
- KMID: 2524121
- J Cancer Prev.
- 2021 Dec;26(4):266-276.
- doi: 10.15430/JCP.2021.26.4.266
Given the high rates of incidence and mortality associated with pancreatic cancer (PanC), there is a need to develop alternative strategies to target PanC. Recent studies have demonstrated that fruits... -
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- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells
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Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK
- KMID: 2395254
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):599-607.
- doi: 10.4196/kjpp.2017.21.6.599
Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased... -
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