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Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease

Jeon YC, Choi JK, Choi EK, Carp RI, Kim YS

Chronic wasting disease (CWD) is classified as a transmissible spongiform encephalopathy or prion disease that affects cervids. CWD has been reported in 15 US states, two Canadian provinces, and in...
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Development of monoclonal antibodies against the abnormal prion protein isoform (PrPres) associated with chronic wasting disease (CWD)

Jeong HJ, Lee NH, Lee JB, Park SY, Song CS, Seo KH, Kim DW, Kim YS, Choi IS

  • KMID: 2392003
  • J Vet Sci.
  • 2012 Dec;13(4):429-432.
Monoclonal antibodies (mAbs) specific for the abnormal prion protein isoform (PrPres) are indispensable for diagnosing chronic wasting disease (CWD). In this study, eight mAbs were developed by immunizing PrP knockout...
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The Study for the Relationship of Weight Loss with Plasma Leptin and TNF-alpha Level in Patients with Chronic Bronchitis and Emphysema

Pack JH, Park JY, Park HJ, Baek SH, Shin KC, Chung JH, Lee KH

BACKGROUND: Unexplained weight loss, which commonly occurs in patients with chronic obstructive pulmonary disease(COPD), is important because weight loss is an independent risk factor of mortality and morbidity in these...
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Serum adiponectin level and cardiovascular disease in patients with end-stage renal disease

Lee HY, Her AY, Choi DW, Park MO, Baek HJ, Jung HH

  • KMID: 2256499
  • Korean J Med.
  • 2006 Dec;71(6):646-653.
BACKGROUND: Adiponectin is a fat-based protein that alters the insulin sensitivity, has anti-inflammatory properties, and reduces the incidence of cardiovascular disease (CVD). However, this connection is unclear in patients with...
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