- Effectiveness and Safety of Dabrafenib in the Treatment of 20 Chinese Children with BRAFV600E-Mutated Langerhans Cell Histiocytosis
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Yang Y, Wang D, Cui L, Ma HH, Zhang L, Lian HY, Zhang Q, Zhao XX, Zhang LP, Zhao YZ, Li N, Wang TY, Li ZG, Zhang R
- KMID: 2510668
- Cancer Res Treat.
- 2021 Jan;53(1):261-269.
- doi: 10.4143/crt.2020.769
Purpose We sought to investigate the effectiveness and safety of dabrafenib in children with BRAFV600E-mutated Langerhans cell histiocytosis (LCH). Materials and Methods A retrospective analysis was performed on 20 children... -
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- Lifestyle Interventions for Non-Obese Patients Both with, and at Risk, of Non-Alcoholic Fatty Liver Disease
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Zhang XL, Wang TY, Targher G, Byrne CD, Zheng MH
- KMID: 2530178
- Diabetes Metab J.
- 2022 May;46(3):391-401.
- doi: 10.4093/dmj.2022.0048
Non-alcoholic fatty liver disease occurring in non-obese subjects (the so-called non-obese NAFLD) is a highly prevalent but neglected liver condition, which is closely associated with metabolic disorders and suboptimal lifestyles.... -
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- ALDH2 Gene: Its Effects on the Neuropsychological Functions in Patients with Opioid Use Disorder Undergoing Methadone Maintenance Treatment
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Lee PW, Wang TY, Chang YH, Lee SY, Chen SL, Wang ZC, Chen PS, Chu CH, Huang SY, Tzeng NS, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB
- KMID: 2502135
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):136-144.
- doi: 10.9758/cpn.2020.18.1.136
Objective: Patients with opioid use disorder (OUD) have impaired attention, inhibition control, and memory function. The aldehyde dehydrogenase 2 (ALDH2 ) gene has been associated with OUD and ALDH2 gene... -
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- Danshensu Interventions Mediate Rapid Antidepressant Effects by Activating the Mammalian Target of Rapamycin Signaling and Brain-Derived Neurotrophic Factor Release
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Chuang HW, Huang CC, Chen KT, Kuo YY, Ren JH, Wang TY, Tsai MH, Chen PT, Wei IH
- KMID: 2560901
- Psychiatry Investig.
- 2024 Nov;21(11):1286-1298.
- doi: 10.30773/pi.2024.0238
Objective Danshensu, a phenylpropanoid compound, is derived from the dry root and rhizome of Danshen (Salvia miltiorrhiza), a traditional Chinese medicinal herb. Evidence suggests that danshensu protects isolated rat hearts... -
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- Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder
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Lu RB, Chang YH, Lee SY, Wang TY, Cheng SL, Chen PS, Yang YK, Hong JS, Chen SL
- KMID: 2502136
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):145-152.
- doi: 10.9758/cpn.2020.18.1.145
Objective: Valproic acid (VPA) is an anticonvulsant and commonly long term used as a mood stabilizer for patients with mood disorders. However its chronic effects on the hematological changes were... -
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