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Expression of Open Reading Frame 5 Protein of Porcine Reproductive and Respiratory Syndrome Virus Using Semliki Forest Virus Expression System

Jung HS, Hwang IW, Kim SM, Kim CJ, Shin KS, Kim HS

  • KMID: 1101569
  • J Vet Sci.
  • 2002 Mar;3(1):13-18.
The ORF5 gene encodes a major envelope glycoprotein (GP5), which is one of the three major proteins of porcine reproductive and respiratory syndrome virus (PRRSV). The GP5 protein has been...
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Hepatitis B Viral Surface Mutations in Patients with Adefovir Resistant Chronic Hepatitis B with A181T/V Polymerase Mutations

Kim JH, Jung YK, Joo MK, Kim JH, Yim HJ, Park JJ, Kim JS, Bak YT, Yeon JE, Byun KS

The hepatitis B virus (HBV) polymerase gene has overlapping reading frames with surface genes, which allows to alter the amino acid codon of the surface genes. In adefovir (ADV) treated...
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Molecular characterization and phylogenetic analysis of pseudorabies virus variants isolated from Guangdong province of southern China during 2013–2014

Fan J, Zeng X, Zhang G, Wu Q, Niu J, Sun B, Xie Q, Ma J

Outbreaks of pseudorabies (PR) have occurred in southern China since late 2011, resulting in significant economic impacts on the swine industry. To identify the cause of PR outbreaks, especially among...
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Genomic diversity of the Avian leukosis virus subgroup J gp85 gene in different organs of an infected chicken

Meng F, Li X, Fang J, Gao Y, Zhu L, Xing G, Tian F, Gao Y, Dong X, Chang S, Zhao P, Cui Z, Liu Z

The genomic diversity of Avian leukosis virus subgroup J (ALV-J) was investigated in an experimentally infected chicken. ALV-J variants in tissues from four different organs of the same bird were...
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Analysis of polymorphic region of GAM-1 gene in Plasmodium vivax Korean isolates

Kho WG, Chung JY, Hwang UW, Chun JH, Park YH, Chung WC

The identification, characterization and quantification of Plasmodium sp. genetic polymorphism are becoming increasingly important in the vaccine development. We investigated polymorphism of Plasmodium vivax GAM-1 (PvGAM-1) gene in 30 Korean...
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Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Abeta pathology and improves cognitive function

Kim TK, Han HE, Kim H, Lee JE, Choi D, Park WJ, Han PL

  • KMID: 1402318
  • Exp Mol Med.
  • 2012 Dec;44(12):740-748.
The plant viral protease, NIa, has a strict substrate specificity for the consensus sequence of Val-Xaa-His-Gln, with a scissoring property after Gln. We recently reported that NIa efficiently cleaved the...
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Molecular characterization of highly pathogenic avian influenza H5N8 viruses isolated from Baikal teals found dead during a 2014 outbreak in Korea

Kim SH, Hur M, Suh JH, Woo C, Wang SJ, Park ER, Hwang J, An IJ, Jo SD, Shin JH, Yu SD, Choi K, Lee DH, Song CS

Nineteen highly pathogenic avian influenza (HPAI) H5N8 viruses were isolated from wild birds in the Donglim reservoir in Gochang, Jeonbuk province, Korea, which was first reported to be an outbreak...
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Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy

Kim EJ, Yoo JY, Choi YH, Ahn KJ, Lee JD, Yun CO, Yun M

PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression...
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