- Angiotensin II-induced aortic ring constriction is mediated by phosphatidylinositol 3-kinase/L-type calcium channel signaling pathway
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Do KH, Kim MS, Kim JH, Rhim BY, Lee WS, Kim CD, Bae SS
- KMID: 1119322
- Exp Mol Med.
- 2009 Aug;41(8):569-576.
- doi: 10.3858/emm.2009.41.8.062
Angiotensin II (AngII) is a crucial hormone that affects vasoconstriction and exerts hypertrophic effects on vascular smooth muscle cells. Here, we showed that phosphatidylinositol 3-kinase-dependent calcium mobilization plays pivotal roles... -
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- Characterization of lnhibition by Nifedipine and Nitroprusside of the Pressor Respones to alpha1-Adrenoceptor Agonists Cirazoline and Sgd 101/75 in Pithed Rats
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Jung HO, Hong KW
- KMID: 1119205
- Yonsei Med J.
- 1988 Jun;29(2):176-184.
- doi: 10.3349/ymj.1988.29.2.176
In this study the effects of two unrelated vasodilators, nifedipine and nitroprusside, on the pressor responsiveness to the 1-adrenoceptor full agonist cirazoline and partial agonist Sgd 101/75 in pithed rats... -
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- Inhibition of Hypoxic Pulmonary Vasoconstriction of Rats by Carbon Monoxide
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Yoo HY, Park SJ, Bahk JH, Kim SJ
- KMID: 2157842
- J Korean Med Sci.
- 2010 Oct;25(10):1411-1417.
- doi: 10.3346/jkms.2010.25.10.1411
Hypoxic pulmonary vasoconstriction (HPV), a unique response of pulmonary circulation, is critical to prevent hypoxemia under local hypoventilation. Hypoxic inhibition of K+ channel is known as an important O2-sensing mechanism... -
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- Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
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Kang YH, Yang IJ, Morgan KG, Shin HM
- KMID: 1402319
- Exp Mol Med.
- 2012 Dec;44(12):749-755.
Cinnamyl alcohol (CAL) is known as an antipyretic, and a recent study showed its vasodilatory activity without explaining the mechanism. Here we demonstrate the vasodilatory effect and the mechanism of... -
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- Effects of adenosine tetraphosphate (ATPP) on vascular tone in the isolated rat aorta
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Lee JW, Kong ID, Park KS, Jeong SW
- KMID: 699860
- Yonsei Med J.
- 1995 Dec;36(6):487-496.
- doi: 10.3349/ymj.1995.36.6.487
Effects of a platelet-released, naturally occurring nucleotide, adenosine 5'-tetraphosphate (ATPP) on vascular tone were analyzed in the isolated rat aorta. Under resting tension ATPP (1 approximately 100 microM) elicited concentration-dependent... -
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- Effects of mastoparan on a vascular contractility in rabbit aorta
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Lee YH, Kang SI, Ahn DS, Lee HY, Choi EJ, Kang BS
- KMID: 1123181
- Yonsei Med J.
- 1995 Jun;36(3):262-270.
- doi: 10.3349/ymj.1995.36.3.262
Mastoparan is an amphiphilic tetradecapeptide derived from wasp venom which activates G-proteins. Several secondary effects have been attributed to this peptide, including activation of phospholipase and phosphatidylinositol kinase. The aim... -
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- Effects of calcium antagonists on contractions of chorionic arteries in normal and preeclampsia placenta
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Kook H, Yoon YD, Baik YH
- KMID: 644958
- J Korean Med Sci.
- 1996 Jun;11(3):250-257.
- doi: 10.3346/jkms.1996.11.3.250
This study was undertaken to observe the effects of organic or inorganic calcium antagonists and to investigate the involvement of cyclic nucleotides in regulating the vascular tone in the chorionic... -
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- Inhibitory Effect of Fentanyl on Phenylephrine-Induced Contraction of the Rat Aorta
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Park KE, Sohn JT, Jeong YS, Sung HJ, Shin IW, Lee HK, Chung YK
- KMID: 1758571
- Yonsei Med J.
- 2009 Jun;50(3):414-421.
- doi: 10.3349/ymj.2009.50.3.414
PURPOSE: Fentanyl was reported to inhibit the alpha1-adrenoceptor agonist-induced contraction. The goal of this in vitro study was to identify the alpha1-adrenoceptor subtype primarily involved in the fentanyl-induced attenuation of... -
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