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Expression of Vascular Endothelial Growth Factor-C in Breast Carcinoma

Chung MJ, Yang SH, Jang KY, Moon WS, Kang MJ, Lee DG

  • KMID: 2073754
  • Korean J Pathol.
  • 2005 Dec;39(6):401-405.
BACKGROUND: Vascular endothelial growth factor-C (VEGF-C) is a novel growth factor that regulates lymphangiogenesis and/or angiogenesis via binding to the vascular endothelial growth factor receptor-3 (VEGFR-3) or VEGFR-2. Recent...
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Establishment and Characterization of Human Lymphatic Endothelial Cell in Breast Cancer Patients Undergoing Sentinel Lymphadenectomy

Takeda A

Recently remarkable progress has been made in the understanding of lymphangiogenesis due to the availability of specific biomarkers. A sentinel lymph node (SLN) biopsy has already been established as a...
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Microvessel and Lymphatic Vessel Density and VEGFR-3 Expression of Papillary Thyroid Carcinoma with Comparative Analysis of Clinicopathological Characteristics

Cheong H, Kang H, Kim HK, Bae JY, Song DE, Cho MS, Sung SH, Han WS, Koo H

  • KMID: 1837527
  • Korean J Pathol.
  • 2010 Jun;44(3):243-251.
BACKGROUND: This study was done to see if there were correlations between anatomic and molecular parameters such as microvessel density (MVD), lymphatic vessel density (LVD), and vascular endothelial growth factor...
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Gene Expression for Lymphangiogenic Factors in Oral Mucosal Squamous Cell Carcinoma

Park YW, Kim SG, Kim SH, Kim HS, Kim MK

  • KMID: 1474262
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2009 Nov;31(6):453-460.
BACKGROUND AND PURPOSE: Vascular endothelial growth factor (VEGF)-C, VEGF-D and their tyrosine kinase receptor, VEGF receptor (VEGFR)-3 are recently known to have lymphangiogenic activities in various tumor types. Oral mucosal...
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Association Between c-Met and Lymphangiogenic Factors in Patients With Colorectal Cancer

Kim HJ, Baek MJ, Kang DH, Lee SC, Bae SB, Lee KT, Lee N, Kim H, Jeong D, Ahn TS, Lee MS, Hong DS, Won JH

PURPOSE: Animal models show a strong relationship between lymphangiogenesis and lymph node metastasis. However, the clinical significance of lymphangiogenesis in patients with colorectal cancer (CRC) remains uncertain. This study aimed...
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Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library

Shi LF, Wu Y, Li CY

OBJECTIVE: Vascular endothelial growth factor (VEGF) interaction with its receptor, VEGFR-3/Flt-4, regulates lymphangiogenesis. VEGFR-3/Flt-4 expression in cancer cells has been correlated with clinical stage, lymph node metastasis, and lymphatic invasion....
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An Experimental Study for Mouse Lymphedema Model

Chung JK, Kwon YJ, Lee TS, Park HS, Yoo YS, Choi GH, Hahn S, Hwang JH, Lee JY

PURPOSE: Lymphedema is a disease with a poorly understood pathogenesis and without definite ways of treatment, yet it can lead to serious complications. The purpose of this study was to...
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