- Differential Expression of Placenta Growth Factors and Their Receptors In the Normal and Pregnancy-Induced Hypertensive Human Placentas
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Cho GJ, Roh GS, Kim HJ, Kim YS, Cho SH, Choi WJ, Paik WY, Kang SS, Choi WS
- KMID: 2157658
- J Korean Med Sci.
- 2003 Jun;18(3):402-408.
- doi: 10.3346/jkms.2003.18.3.402
Placental development requires extensive angiogenesis and the invasion of the maternal decidua by the trophoblasts. Adequate and organized interaction of vascular endothelial growth factors (VEGF), placenta growth factors (PlGF), and... -
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- Association of Vascular Endothelial Growth Factor Gene Polymorphisms with Susceptibility and Clinicopathologic Characteristics of Colorectal Cancer
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Chae YS, Kim JG, Sohn SK, Cho YY, Ahn BM, Moon JH, Jeon SW, Park JY, Lee IT, Choi GS, Jun SH
- KMID: 1786879
- J Korean Med Sci.
- 2008 Jun;23(3):421-427.
- doi: 10.3346/jkms.2008.23.3.421
Since vascular endothelial growth factor (VEGF) is known to be a potent pro-angiogenic factor, we evaluated the potential association of two VEGF gene polymorphisms (-634G>C and 936C>T) with the susceptibility... -
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- Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer
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Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS
- KMID: 756286
- Exp Mol Med.
- 2009 Jan;41(1):51-58.
- doi: 10.3858/emm.2009.41.1.007
Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution... -
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- Gender-specific Association between Polymorphism of Vascular Endothelial Growth Factor (VEGF 936C>T) Gene and Patients with Stomach Cancer
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Bae SJ, Ahn DH, Hong SP, Kang H, Hwang SG, Oh D, Kim NK
- KMID: 2158197
- Yonsei Med J.
- 2008 Oct;49(5):783-791.
- doi: 10.3349/ymj.2008.49.5.783
PURPOSE: Angiogenesis plays an important role in the growth, progression, and metastasis of tumors. Vascular endothelial growth factor (VEGF) overexpression has been associated with advanced stage and poor survival in... -
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- Cardiac expression profiles of the naked DNA vectors encoding vascular endothelial growth factor and basic fibroblast growth factor
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Lee JS, Byun J, Kim JM, Kim CY, Kim BM, Chung JH, Jang Y, Kim DK
- KMID: 1089454
- Exp Mol Med.
- 2005 Oct;37(5):447-456.
We investigated expression profiles and biological effects of the naked DNA vectors in the heart. To this end, naked DNA vector was injected into the apex of the beating rat... -
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- VEGF Promoter Polymorphism Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese Population
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Zhuo Y, Zeng Q, Zhang P, Li G, Xie Q, Cheng Y
- KMID: 2427118
- Yonsei Med J.
- 2017 Mar;58(2):305-311.
- doi: 10.3349/ymj.2017.58.2.305
PURPOSE: Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS: In this study, we hypothesized that single nucleotide variants in... -
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- The Different Effect of VEGF Polymorphisms on the Prognosis of Non-Small Cell Lung Cancer according to Tumor Histology
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Lee S, Kang HG, Choi JE, Lee JH, Kang HJ, Baek SA, Lee E, Seok Y, Lee WK, Lee SY, Yoo SS, Lee J, Cha SI, Kim CH, Cho S, Park JY
- KMID: 2470268
- J Korean Med Sci.
- 2016 Nov;31(11):1735-1741.
- doi: 10.3346/jkms.2016.31.11.1735
Vascular endothelial growth factor (VEGF) contributes to tumor angiogenesis. The role of VEGF single nucleotide polymorphisms (SNPs) in lung cancer susceptibility and its prognosis remains inconclusive and controversial. This study... -
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- Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease
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Kim HJ, Jang SY, Park JI, Byun J, Kim DI, Do YS, Kim JM, Kim S, Kim BM, Kim WB, Kim DK
- KMID: 1094077
- Exp Mol Med.
- 2004 Aug;36(4):336-344.
This phase 1 clinical trial tested the safety of intramuscular gene transfer by using naked plasmid DNA encoding the gene for VEGF, and analyzed the potential therapeutic benefits in patients... -
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