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Platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer

Takekuma M, Kuji S, Tanaka A, Takahashi , Abe M, Hirashima

OBJECTIVE: The concept of platinum sensitivity and cross-resistance among platinum agents are widely known in the management of recurrent ovarian cancer. The aim of this study was to evaluate two...
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High-dose oral tegafur-uracil maintenance therapy in patients with uterine cervical cancer

Sakaguchi , Motohara T, Saito F, Takaishi K, Fukumatsu , Tohya T, Shibata S, Mimori H, Tashiro H, Katabuchi

OBJECTIVE: The aim of this study was to determine the efficacy and toxicity of oral administration of tegafur-uracil (UFT) at a high dose, 600 mg/day, based on the tegafur dose,...
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Efficacy and tolerability of paclitaxel, ifosfamide, and cisplatin as a neoadjuvant chemotherapy in locally advanced cervical carcinoma

Scandurra , Scibilia G, Banna GL, D'Agate G, Lipari H, Gieri S, Scollo P

OBJECTIVE: To evaluate the efficacy and tolerability of a neoadjuvant paclitaxel, ifosfamide, and cisplatin chemotherapy in patients with locally advanced cervical carcinoma. METHODS: Patients with histologically confirmed locally advanced cervical carcinoma,...
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