- The Role of N-Acetyl Transferases on Isoniazid Resistance from Mycobacterium tuberculosis and Human: An In Silico Approach
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Unissa AN, Sukumar S, Hanna LE
- KMID: 2385040
- Tuberc Respir Dis.
- 2017 Jul;80(3):255-264.
- doi: 10.4046/trd.2017.80.3.255
BACKGROUND: N-acetyl transferase (NAT) inactivates the pro-drug isoniazid (INH) to N-acetyl INH through a process of acetylation, and confers low-level resistance to INH in Mycobacterium tuberculosis (MTB). Similar to NAT... -
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