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Pathophysiology of Diabetic Retinopathy: The Old and the New

Kusuhara S, Fukushima , Ogura S, Inoue N, Uemura A

Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to anatomical and functional alterations in retinal neurons and glial cells....
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Clip ligation for treatment of patent ductus arteriosus occlusion in three cats

Ozai Y, Uemura A, Tanaka R, Takeuchi A, Hamabe L, Shimada K, Yokoi A, Hirose M, Watanabe M, Uehara K

Patent ductus arteriosus (PDA) is a rare congenital cardiovascular anomaly in cats. Due to their small body, intercostal thoracotomy is the most common option to close the PDA. However, few reports...
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Unruptured right sinus of Valsalva aneurysm in a Maltese dog: a case report

Uemura A, Tanaka R, Nakata TM, Namiki R, Tanaka T, Matsuura K, Yoshida T

A rare case of an unruptured sinus of Valsalva aneurysm (SVA) in a 2-month-old male Maltese terrier weighing 1.0 kg with a heart murmur is presented. A right SVA and...
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Hybrid balloon dilation treatment for cor triatriatum dexter in a small breed puppy

Uemura A, Yoshida T, Matsuura K, Yilmaz Z, Tanaka R

The authors encountered a 4-month-old, female Shiba dog weighing 4.0 kg, who had been exhibiting abdominal distension and increasing ascites for 2 months. She was brought for further examination and...
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Identification of Novel Drug Targets for the Treatment of Diabetic Retinopathy

Uemura A

Vision loss in diabetic retinopathy (DR) is attributable to retinal vascular disorders that result in macular edema and neoangiogenesis. In addition to laser photocoagulation therapy, intraocular injections of antivascular endothelial...
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Surgical outcomes in dogs with tracheal collapse treated with a novel crossand-hook braided endoluminal stent

Uemura A, Ozai Y, Hamabe L, Yoshida T, Tanaka R

Background: Stenting is an effective treatment option for tracheal collapse in dogs. Crossbraided tracheal stents are currently the norm in veterinary medicine, but cross-and-hook braided stents have recently been adopted...
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Impact of Extra-Corporeal Membrane Oxygenation and Blood Purification Therapy on Early Mobilization in the Intensive Care Unit: Retrospective Cohort Study

Watanabe S, Iida Y, Hirasawa J, Naito Y, Mizutani M, Uemura A, Nishimura S, Suzuki K, Morita Y

Objective: To investigate the effect on early mobilization in patients undergoing extra-corporeal membrane oxygenation (ECMO) and acute blood purification therapy in the intensive care unit (ICU). Methods: We conducted this multicenter...
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