- Microarray Analysis for Genes Associated with Angiogenesis in Diabetic OLETF Keratocytes
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Park JM, Park YM, Jung W, Lee JE, Lee JS
- KMID: 1789986
- J Korean Med Sci.
- 2014 Feb;29(2):265-271.
- doi: 10.3346/jkms.2014.29.2.265
The purpose of this study was to identify the differences in angiogenesis gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). Primarily cultured... -
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- Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
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Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE
- KMID: 2352817
- Yonsei Med J.
- 2015 Jan;56(1):277-286.
- doi: 10.3349/ymj.2015.56.1.277
PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs... -
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- Microarray for Genes Associated with Signal Transduction in Diabetic OLETF Keratocytes
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Lee JE, Lee JS, Hwang SH
- KMID: 1101914
- Korean J Ophthalmol.
- 2007 Jun;21(2):111-119.
- doi: 10.3341/kjo.2007.21.2.111
PURPOSE: The purpose of this study was to identify differences in signal transduction gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). ... -
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- Cobalt Chloride Attenuates Oxidative Stress and Inflammation through NF-kappaB Inhibition in Human Renal Proximal Tubular Epithelial Cells
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Oh SW, Lee YM, Kim S, Chin HJ, Chae DW, Na KY
- KMID: 2069805
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S139-S145.
- doi: 10.3346/jkms.2014.29.S2.S139
We evaluated the effect of cobalt chloride (CoCl2) on TNF-alpha and IFN-gamma-induced-inflammation and reactive oxygen species (ROS) in renal tubular epithelial cells (HK-2 cells). We treated HK-2 cells with CoCl2... -
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- B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation
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Kim YH, Choi BH, Cheon HG, Do MS
- KMID: 1123468
- Exp Mol Med.
- 2009 Mar;41(3):208-216.
- doi: 10.3858/emm.2009.41.3.024
B cell activation factor (BAFF) is a novel member of the TNF ligand superfamily, mainly produced by myeloid cells. BAFF has been shown to participate in B-cell survival and B-... -
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- Expression and Regulation of Osteoprotegerin in Adipose Tissue
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An JJ, Han DH, Kim DM, Kim SH, Rhee Y, Lee EJ, Lim SK
- KMID: 1122612
- Yonsei Med J.
- 2007 Oct;48(5):765-772.
- doi: 10.3349/ymj.2007.48.5.765
PURPOSE: Osteoprotegerin (OPG), a potent inhibitor of osteoclastic bone resorption, has a variety of biological functions that include anti-inflammatory effects. Adipocytes and osteoblasts share a common origin, and the... -
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- Eupatilin Ameliorates Collagen Induced Arthritis
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Kim J, Kim Y, Yi H, Jung H, Rim YA, Park N, Jung SM, Park SH, Ju JH
- KMID: 2133298
- J Korean Med Sci.
- 2015 Mar;30(3):233-239.
- doi: 10.3346/jkms.2015.30.3.233
Eupatilin is the main active component of DA-9601, an extract from Artemisia. Recently, eupatilin was reported to have anti-inflammatory properties. We investigated the anti-arthritic effect of eupatilin in a murine... -
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- Myeloid differentiation primary response protein 88 blockade upregulates indoleamine 2,3-dioxygenase expression in rheumatoid synovial fibroblasts
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Park MK, Oh HJ, Heo YM, Park EM, Cho ML, Kim HY, Park SH
- KMID: 1022119
- Exp Mol Med.
- 2011 Aug;43(8):446-454.
- doi: 10.3858/emm.2011.43.8.050
Indoleamine 2,3-dioxygenase (IDO) is a key negative regulator of immune responses and has been implicated in tumor tolerance, autoimmune disease and asthma. IDO was detected in the joint synovial tissue... -
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- In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors
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Baek SJ, Kang SK, Ra JC
- KMID: 1123372
- Exp Mol Med.
- 2011 Oct;43(10):596-603.
- doi: 10.3858/emm.2011.43.10.069
The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have stimulated intravenous applications for their use in stem cell therapy. However, the soluble factors and corresponding cellular receptors responsible... -
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- Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells
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Pae HO, Jeong GS, Jeong SO, Kim HS, Kim SA, Kim YC, Yoo SJ, Kim HD, Chung HT
- KMID: 1047077
- Exp Mol Med.
- 2007 Jun;39(3):267-277.
In vascular smooth muscle cells (VSMCs), induction of the heme oxygenase-1 (HO-1) confers vascular protection against cellular proliferation mainly via its up-regulation of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) that is... -
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- Impaired responses of leukemic dendritic cells derived from a human myeloid cell line to LPS stimulation
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Kim KD, Choi SC, Noh YW, Kim JW, Paik SG, Yang Y, Kim KI, Lim JS
- KMID: 1105279
- Exp Mol Med.
- 2006 Feb;38(1):72-84.
Several myeloid leukemia-derived cells have been reported to possess the ability to differentiate into dendritic cells (DC). MUTZ-3, a myeloid leukemia cell line, responds to GM-CSF, IL-4 and TNF-alpha, and... -
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- 5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion
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Choi JH, Park JG, Jeon HJ, Kim MS, Lee MR, Lee MN, Sonn S, Kim JH, Lee MH, Choi MS, Park YB, Kwon OS, Jeong TS, Lee WS, Shim HB, Shin DH, Oh GT
- KMID: 1022122
- Exp Mol Med.
- 2011 Aug;43(8):471-478.
- doi: 10.3858/emm.2011.43.8.053
A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy-2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of... -
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