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Induction of nitric oxid esynthase(NOS) by soluble glucocorticoid induced tumor necrosis factor receptor(sGITR) is modulated by IFN-g in murine macrophage

Shin HH, Lee HW, Choi HS

  • KMID: 1094698
  • Exp Mol Med.
  • 2003 Jun;35(3):175-180.
Earlier study showed that glucocorticoid induced tumor necrosis factor receptor (GITR), a new TNFR family, activated murine macrophages to express inducible nitric oxide synthase (iNOS) and to generate nitric oxide...
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The Origin of Proinflammatory Cytokines in Patients with Idiopathic Dilated Cardiomyopathy

Chang HJ, Chung J, Choi BJ, Choi TY, Choi SY, Yoon MH, Hwang GS, Shin JH, Tahk SJ, Choi BI

Proinflammatory cytokines and their receptors are increased in the peripheral blood of patients with heart failure. We measured cytokines and their receptors in systemic artery (SA), coronary sinus (CS) and...
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Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway

Kim DJ, Chung JH, Ryu EK, Rhim JH, Ryu YS, Park SH, Kim KT, Kang HS, Chung HK, Park SC

  • KMID: 1110124
  • Exp Mol Med.
  • 2006 Aug;38(4):401-407.
Although the apoptosis of chondrocytes plays an important role in endochondral ossification, its mechanism has not been elucidated. In this study, we show that guanosine induces chondrocyte apoptosis based on...
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Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice

Shin HH, Kim SG, Lee MH, Suh JH, Kwon BS, Choi HS

  • KMID: 1093607
  • Exp Mol Med.
  • 2003 Oct;35(5):358-364.
Glucocorticoid-induced TNF receptor (GITR) was a new member of the TNF/nerve growth factor receptor (TNFR/ NGFR) family and induced in murine T cells by dexamathasone. Recombinant soluble GITR (sGITR) induced...
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