- The Role of Extracellular-signal-regulated Kinase and p38 in Trypsinogen Activation in Cerulein-Stimulated Rat Pancreatic Acini
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Hwang JH, Kim YJ, Kim J, Jeong JB, Kim YT, Yoon YB, Kim CY
- KMID: 1647122
- Korean J Gastroenterol.
- 2002 Oct;40(4):263-267.
BACKGROUND/AIMS: Intra-acinar cell activation of trypsinogen is a critical event in cerulein-induced pancreatitis. However, little is known about the intracellular signal transduction system that is involved in this process. The... -
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- The Role of Nuclear Factor kB and Phosphatidylinositol 3 - kinase in Trypsinogen Activation in Cerulein - Stimulated Rat Pancreatic Acini
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Kim YJ, Kim YT, Hwang JH, Kim J, Jeong JB, Yoon YB, Kim CY
- KMID: 2085005
- Korean J Gastroenterol.
- 2001 Dec;38(6):427-432.
BACKGROUND/AIMS: Intra-acinar cell activation of trypsinogen is a critical event in cerulein-induced pancreatitis. However, little is known about the intracellular signal transduction systems involved in trypsinogen activation. This study focused... -
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- Usefulness of Urinary Trypsinogen-2 Dipstick Test for Diagnosis of Acute Pancreatitis
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Hwang SJ, Chung JP, Kim YG, Song DH, Lee JS, Baek SS, Kim DY, Lee DY, Jeong YS, Ji SW, Lee SJ, Song SY, Lee KS, Chung JB, Lee SI, Kang JK, Park JS, Cho KH
- KMID: 772651
- Korean J Gastroenterol.
- 2004 Jun;43(6):364-369.
BACKGROUND/AIMS: The clinical usefulness of urinary trypsinogen-2 dipstick test is still in controversy. We evaluated the usefulness of urinary trypsinogen-2 dipstick test in patients with acute pancreatitis. METHODS: Urinary... -
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- Cationic Trypsinogen Gene Mutation in Patients with Chronic Idiopathic Pancreatitis
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Lee WJ, Kim KA, Lee JS, Jeon YB, Jeong JB, Ryu JK, Kim YT, Yoon YB, Kim CY
- KMID: 1111508
- Korean J Gastroenterol.
- 2004 Jan;43(1):41-46.
BACKGROUND/AIMS: Mutation of Cationic trypsinogen gene is clearly associated with hereditary pancreatitis and plays an important role in the pathogenesis of pancreatitis. According to literature, this mutation is occasionally... -
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- A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene
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Shin JY, Oh DS, Rheu JM, Shim JO, Park JS, Ko JS, Seo JK
- KMID: 2279790
- Korean J Pediatr.
- 2006 Oct;49(10):1111-1115.
- doi: 10.3345/kjp.2006.49.10.1111
Hereditary pancreatitis is an autosomal dominant disease characterized by recurrent episodes of pancreatitis, often beginning in childhood, with a positive family history involving at least two other affected family members... -
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- Pathogenesis of Acute Pancreatitis
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Oh TG, Bang S
- KMID: 2267800
- Korean J Med.
- 2013 Aug;85(2):111-115.
Acute pancreatitis is an inflammatory disease that is caused by various etiologies including gallstone, alcohol or hypertriglyceridemia. Although most cases of acute pancreatitis show self-limiting course, severe cases are still... -
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- Three Cases of Hereditary Pancreatitis in Two Households in the Same Family Associated with R122H Mutation in Cationic Trypsinogen Gene
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Lee TY, Oh HC, Kim MH, Kwon S, Lee SS, Seo DW, Lee SK
- KMID: 782877
- Korean J Gastroenterol.
- 2007 Jun;49(6):395-399.
Hereditary pancreatitis is a rare, autosomal dominant, inherited disease characterized by recurrent attacks of acute pancreatitis with the development of chronic pancreatitis and an increased risk of pancreatic cancer. R122H... -
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- Hereditary Pancreatitis: Report of a Kindred
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Kim HR, Chung JH, Song YT, Yoon WJ, Ryu JK, Kim YT
- KMID: 2427248
- J Korean Assoc Pediatr Surg.
- 2006 Jun;12(1):24-31.
Hereditary pancreatitis (HP) appears as an autosomal dominant trait. If the patient has (1) more than 2 affected relatives in different generations and (2) no known etiological factors such as... -
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- Hereditary Pancreatitis
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Lee SK
- KMID: 772858
- Korean J Gastroenterol.
- 2005 Nov;46(5):358-367.
The first family of hereditary pancreatitis was described in 1952. The mode of inheritance is autosomal dominant trait with an 80% of penetrance rate. Although hereditary pancreatitis is rare, this... -
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- Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation
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Rho ES, Kim E, Koh H, Yoo HW, Lee BH, Kim GH
- KMID: 2284841
- Korean J Pediatr.
- 2013 May;56(5):227-230.
- doi: 10.3345/kjp.2013.56.5.227
Chronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually produce endocrine insufficiency. Some causes of chronic pancreatitis appear to... -
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- The Role of Heat Shock Protein 70 in the Pancreatic Trypsinogen Activation: Studies in Hsp70.1 Knock-out Mice
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Hwang JH, Kim YT, Yoon YB, Jeong JB, Bae CJ, Seo JS, Kim CY
- KMID: 1647238
- Korean J Gastroenterol.
- 2002 Nov;40(5):326-333.
BACKGROUND/AIMS: Heat shock proteins (Hsps) are expressed in the cell as a response to the external stimulation such as heat. There are some reports that the Hsp (i.e. Hsp70) is... -
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- A Case of R122H Mutation of Cationic Trypsinogen Gene in a Pediatric Patient with Hereditary Pancreatitis Complicated by Pseudocyst and Hemosuccus Pancreaticus
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Kim JY, Choi SH, Ihm JS, Kim SJ, Kim IJ, Kim CM
- KMID: 2439748
- Korean J Gastroenterol.
- 2005 Feb;45(2):130-136.
Hereditary pancreatitis is a rare autosomal dominant inherited disease with 80% penetration rate. The disease is characterized by recurrent episodes of pancreatitis often beginning in childhood, positive family history with... -
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- Hereditary Pancreatitis
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Kim YT
- KMID: 2439750
- Korean J Gastroenterol.
- 2005 Feb;45(2):143-147.
Hereditary pancreatitis (HP) is an autosomal dominant inherited disease characterized by recurrent episodes of pancreatitis often beginning in childhood, a family history of at least 2 other affected members, and... -
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- Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis
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Kim JN, Lee HS, Ryu SH, Kim YS, Moon JS, Kim CD, Chang IY, Yoon SP
- KMID: 2284244
- Gut Liver.
- 2011 Dec;5(4):513-520.
BACKGROUND/AIMS: Heat shock proteins (HSPs) protect rats from cerulein-induced acute pancreatitis (AP) by preventing the subcellular redistribution of cathepsin B and the activation of trypsinogen. Autophagy plays a critical role... -
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- Mutations of SPINK1 and PRSS1 Gene in Korean Patients with Chronic Pancreatitis
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Lee KH, Yoon WJ, Ryu JK, Kim YT, Yoon YB, Kim CY
- KMID: 1113323
- Korean J Gastroenterol.
- 2004 Aug;44(2):93-98.
BACKGROUND/AIMS: It has been found that mutations of cationic trypsinogen gene (PRSS1) and serine protease inhibitor, Kazal type 1 gene (SPINK1) increase the susceptibility of chronic pancreatitis (CP). Specifically,... -
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