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Simultaneous Determination of 11 Marker Compounds in Gumiganghwal-tang by HPLC-DAD and LC-MS

Weon JB, Jung YS, Ryu G, Yang WS, Ma CJ

Gumiganghwal-tang has been used for the treatment of common cold for a long-time. We developed an accurate and sensitive high performance liquid chromatography-diode array detection (HPLC-DAD) and electrospray ionization mass...
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Phytochemical Analysis of the Phenolic Fat-Suppressing Substances in the Leaves of Lactuca raddeana in 3T3-L1 Adipocytes

Nugroho A, Choi JS, An HJ, Park HJ

Lactuca raddeana (Compositae) is used to treat obesity and complications due to diabetes. The five phenolic compounds including chlorogenic acid, chicoric acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, luteolin were qualitatively identified...
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Rapid Isolation of Cyanidin 3-Glucoside and Peonidin 3-Glucoside from Black Rice (Oryza sativa) Using High-Performance Countercurrent Chromatography and Reversed-Phase Column Chromatography

Jeon H, Choi J, Choi SJ, Lee CU, Yoon SH, Kim J, Yoon KD

Anthocyanins are water soluble plant pigments which are responsible for the blue, red, pink, violet colors in several plant organs such as flowers, fruits, leaves and roots. In recent years,...
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A Case of Chemical Burn Caused by Trifluoroacetic Anhydride that Mimicked a Hydrofluoric Acid Burn

Park JS, Kim H, Lee SW

  • KMID: 2204099
  • J Korean Soc Clin Toxicol.
  • 2010 Jun;8(1):43-45.
A 22-year-old woman was referred to our emergency department for the treatment of a chemical injury on her arm. She had accidentally spilled 99% trifluoroacetic anhydride (TFAA) over her left...
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Liver Function and Inhaled Anesthetics

Nam SH

The liver is the major site of endogenous and exogenous drug metabolism. The primary result of drug metabolism is the production of more water-soluble and therefore more easily excreted drug...
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Influence of Bradykinin on Catecholamine Release from the Rat Adrenal Medulla

Lim DY, Kim IH, Na GM, Kang MJ, Kim OM, Choi DH, Ki YW

  • KMID: 2285292
  • Korean J Physiol Pharmacol.
  • 2003 Aug;7(4):231-238.
The present study was undertaken to investigate the effect of bradykinin on secretion of catecholamines (CA) evoked by stimulation of cholinergic receptors and membrane depolarization from the isolated perfused model...
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The Effect of Trifluoroacetic Acid, a Metabolite of Isoflurane on the ATP-sensitive Potassium Channel in Rabbit Ventricular Myocytes

Lee DJ, Kim SJ, Ha KH, Kim MC, Cho KH

BACKGROUND: Activation of ATP-sensitive K+ channels (KATP channels) in the cardiac muscle produces cardioprotective effects during myocardial ischemia. Previous experimental evidence indicates that volatile anesthetics exert beneficial actions in ischemic...
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Activation of ATP-sensitive potassium channels by the predominant metabolite of isoflurane in rabbit ventricular myocytes

Han J, Kim NR, Kim EY, Kim SJ, Cho KH

  • KMID: 2285237
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):165-175.
Background: Recent in vivo experimental evidence suggests that isoflurane-induced cardioprotection may involve KATP channel activation. However, it was demonstrated that isofluran inhibited KATP channel activities in the inside-out patch mode. To explain this discrepancy,...
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