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Exploring the Potential of Flunarizine for Cisplatin-Induced Painful Uremic Neuropathy in Rats

Muthuraman A, Singla SK, Peters A

  • KMID: 2232807
  • Int Neurourol J.
  • 2011 Sep;15(3):127-134.
PURPOSE: The present study was designed to explore the potential of flunarizine for cisplatin induced painful uremic neuropathy in rats. METHODS: Cisplatin (2 mg/kg; i.p., for 5 consecutive days) was administered...
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Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes

Kim Y, Kim EY, Seo YM, Yoon TK, Lee WS, Lee KA

OBJECTIVE: Previously, we identified that transketolase (Tkt), an important enzyme in the pentose phosphate pathway, is highly expressed at 2 hours of spontaneous maturation in oocytes. Therefore, this study was...
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Effect of Benfotiamine on the Expression of Phosphodiesterase Type 5 and Its Isoforms in Type 2 Diabetic Rat Kidneys

Shim JB, Yang DY, Han YK, Lee SJ, Kim HJ, Jung HC, Kim SY, Kim HY, Lee YJ

  • KMID: 2298740
  • Korean J Androl.
  • 2010 Aug;28(2):93-99.
PURPOSE: The phosphodiesterases (PDEs) are critical components in the cyclic AMP/protein kinase A and the cyclic GMP/phosphokinase G signaling pathways. The cAMP and cGMP pathways are regulated by activation and...
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