- A Novel Therapeutic Target in Inflammatory Uveitis: Transglutaminase 2 Inhibitor
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Sohn J, Chae JB, Lee SY, Kim SY, Kim JG
- KMID: 1098790
- Korean J Ophthalmol.
- 2010 Feb;24(1):29-34.
- doi: 10.3341/kjo.2010.24.1.29
PURPOSE: Our goal was to investigate the effects of inhibition of transglutaminase 2 (TGase 2) on endotoxin-induced uveitis (EIU) METHODS: EIU was induced in female Lewis rats by single footpad... -
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- Effects of Transglutaminase 2 Inhibition on Ventilator-Induced Lung Injury
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Suh IB, Yoon DW, Oh WO, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Lee SY, Shin C, Shim JJ, In KH, Kang KH, Kim JH
- KMID: 1774462
- J Korean Med Sci.
- 2014 Apr;29(4):556-563.
- doi: 10.3346/jkms.2014.29.4.556
This study was performed to examine the role of transglutaminase 2 (TG2) in ventilator-induced lung injury (VILI). C57BL/6 mice were divided into six experimental groups: 1) control group; 2) lipopolysaccharide... -
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- Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine
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Jeon JH, Lee HJ, Jang GY, Kim CW, Shin DM, Cho SY, Yeo EJ, Park SC, Kim IG
- KMID: 1103326
- Exp Mol Med.
- 2004 Dec;36(6):576-581.
The treatment of cystamine, a transglutaminase (TGase) inhibitor, has beneficial effects in several diseases including CAG-expansion disorders and cataract. We compared the inhibition characteristics of cystamine with those of cysteamine,... -
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