- Loss of Integrity: Impairment of the Blood-brain Barrier in Heavy Metal-associated Ischemic Stroke
-
Kim JH, Byun HM, Chung EC, Chung HY, Bae ON
- KMID: 2317830
- Toxicol Res.
- 2013 Sep;29(3):157-164.
Although stroke is one of the leading causes of death and disability worldwide, preventive or therapeutic options are still limited. Therefore, a better understanding of the pathophysiological characteristics of this... -
- CITED
-
- Close
- SHARE
-
- Close
- Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay
-
Kim JW, Ahn I, Ryu SH, Jeon HR, Lee BS, Kim KB
- KMID: 2317838
- Toxicol Res.
- 2013 Sep;29(3):217-219.
Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan cilexetil is a new antihypertensive drug associated with angiotensin II... -
- CITED
-
- Close
- SHARE
-
- Close
- Recent Updates on Acetaminophen Hepatotoxicity: The Role of Nrf2 in Hepatoprotection
-
Gum SI, Cho MK
- KMID: 2317831
- Toxicol Res.
- 2013 Sep;29(3):165-172.
Acetaminophen (APAP) known as paracetamol is the main ingredient in Tylenol, which has analgesic and anti-pyretic properties. Inappropriate use of APAP causes major morbidity and mortality secondary to hepatic failure.... -
- CITED
-
- Close
- SHARE
-
- Close
- Structural Aspects of GPCR-G Protein Coupling
-
Chung KY
- KMID: 2317829
- Toxicol Res.
- 2013 Sep;29(3):149-155.
G protein-coupled receptors (GPCRs) are membrane receptors; approximately 40% of drugs on the market target GPCRs. A precise understanding of the activation mechanism of GPCRs would facilitate the development of... -
- CITED
-
- Close
- SHARE
-
- Close
- Investigation of Water Safety in Non-treated Drinking Water with Trace Toxic Metals
-
Ly SY, Kim DH, Lee GE
- KMID: 2317837
- Toxicol Res.
- 2013 Sep;29(3):211-215.
The trace toxic metal copper was assayed using mercury immobilized on a carbon nanotube electrode (MCW), with a graphite counter and a reference electrode. In this study, a macro-scale convection... -
- CITED
-
- Close
- SHARE
-
- Close
- Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of epsilon-Acetamidocaproic Acid in Rat Plasma
-
Kim TH, Choi YS, Choi YH, Kim YG
- KMID: 2317836
- Toxicol Res.
- 2013 Sep;29(3):203-209.
A simple and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of epsilon-acetamidocaproic acid (AACA), the primary metabolite of zinc acexamate (ZAC), in rat... -
- CITED
-
- Close
- SHARE
-
- Close
- Hepatotoxicity in Rats Treated with Dimethylformamide or Toluene or Both
-
Kim KW, Chung YH
- KMID: 2317834
- Toxicol Res.
- 2013 Sep;29(3):187-193.
The effects of toluene in dimethylformamide (DMF)-induced hepatotoxicity were investigated with respect to the induction of cytochrome P-450 (CYP) and the activities of related enzymes. The rats were treated intraperitoneally... -
- CITED
-
- Close
- SHARE
-
- Close
- Aluminum Nanoparticles Induce ERK and p38MAPK Activation in Rat Brain
-
Kwon JT, Seo GB, Jo E, Lee M, Kim HM, Shim I, Lee BW, Yoon BI, Kim P, Choi K
- KMID: 2317833
- Toxicol Res.
- 2013 Sep;29(3):181-185.
Aluminum nanoparticles (Al-NPs) are one of the most widely used nanomaterial in cosmetics and medical materials. For this reason, Al-NP exposure is very likely to occur via inhalation in the... -
- CITED
-
- Close
- SHARE
-
- Close
- Gastrointestinal Tract Abnormalities Induced by Prenatal Valproic Acid Exposure in Rat Offspring
-
Kim JW, Choi CS, Kim KC, Park JH, Seung H, Joo SH, Yang SM, Shin CY, Park SH
- KMID: 2317832
- Toxicol Res.
- 2013 Sep;29(3):173-179.
In-utero exposure to valproic acid (VPA) has been known as a potent inducer of autism spectrum disorder (ASD), not only in humans, but also in animals. In addition to the... -
- CITED
-
- Close
- SHARE
-
- Close
- Anti-inflammatory Effect of Isaria sinclairii Glycosaminoglycan in an Adjuvant-treated Arthritis Rat Model
-
Ahn MY, Jee SD, Hwang JS, Yun EY, Ahn KS, Kim YS
- KMID: 2317835
- Toxicol Res.
- 2013 Sep;29(3):195-201.
The anti-inflammatory effects of glycosaminoglycan (GAG) derived from Isaria sinclairii (IS) and of IS extracts were investigated in a complete Freund's adjuvant (CFA)-treated chronic arthritis rat model. Groups of rats... -
- CITED
-
- Close
- SHARE
-
- Close
