- Single-Dose Oral Toxicity of Fermented Scutellariae Radix Extract in Rats and Dogs
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Kim MS, Ham SH, Kim JH, Shin JE, Oh J, Kim TW, Yun HI, Lim JH, Jang BS, Cho JH
- KMID: 1432310
- Toxicol Res.
- 2012 Dec;28(4):263-268.
The aim of this study was to investigate the acute oral toxicity of fermented Scutellariae Radix (JKTMHGu-100) in rats and dogs. JKTM-HGu-100 was orally administered at a dose of 2,000... -
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- Anti-inflammatory Effect of Bumblebee Alcohol Extracts in CFA-Induced Rat Edema
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Ahn MY, Han JW, Yoon HJ, Hwang JS, Young YE
- KMID: 1432308
- Toxicol Res.
- 2012 Dec;28(4):249-253.
In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. terrestris, and B. h. sapporoensis, and tested the anti-inflammatory activity of... -
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- Nasal and Pulmonary Toxicity of Titanium Dioxide Nanoparticles in Rats
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Kwon S, Yang YS, Yang HS, Lee J, Kang MS, Lee BS, Lee K, Song CW
- KMID: 1432304
- Toxicol Res.
- 2012 Dec;28(4):217-224.
In recent decades, titanium dioxide (TiO2) nanoparticles have been used in various applications, including paints, coatings, and food. However, data are lacking on the toxicological aspects associated with their use.... -
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- Biodistribution of 99mTc Tricarbonyl Glycine Oligomers
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Jang BS, Lee JS, Rho JK, Park SH
- KMID: 1432306
- Toxicol Res.
- 2012 Dec;28(4):235-240.
99mTc tricarbonyl glycine monomers, trimers, and pentamers were synthesized and evaluated for their radiolabeling and in vivo distribution characteristics. We synthesized a 99mTc-tricarbonyl precursor with a low oxidation state (I).... -
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- The Effects of Hazardous Chemical Exposure on Cardiovascular Disease in Chemical Products Manufacturing Workers
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Kim KW, Won YL, Ko KS, Heo KH, Chung YH
- KMID: 1432311
- Toxicol Res.
- 2012 Dec;28(4):269-277.
The purpose of this study was to understand the mechanism of cardiovascular disease (CVD) caused by exposure to hazardous chemicals. We investigated changes in the symptoms of metabolic syndrome, which... -
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- A 6-Week Oral Toxicity Study of Oral Cholera Vaccine in Sprague-Dawley Rats
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Baek YO, Choi SK, Shin SH, Koo KH, Choi HY, Cha SB, Li YC, Yoo HJ, Lee JY, Kil KH, Kim HS, Kang MS, Kang BH, Kim KH, Bae JS
- KMID: 1432305
- Toxicol Res.
- 2012 Dec;28(4):225-233.
The present study was carried out to examine the toxicity and target organs of oral cholera vaccine (OCV) after repeated oral administration in Sprague-Dawley rats for 6 weeks (3 administrations,... -
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- The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages
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Kang GJ, Kang NJ, Han SC, Koo DH, Kang HK, Yoo BS, Yoo ES
- KMID: 1432309
- Toxicol Res.
- 2012 Dec;28(4):255-262.
Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, PGE2, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a... -
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- Biocompatible Dispersion Methods for Carbon Black
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Kim H, Park K, Lee MY
- KMID: 1432303
- Toxicol Res.
- 2012 Dec;28(4):209-216.
The biological activity of particles is largely dependent on their size in biological systems. Dispersion in the aqueous phase has been both a critical impediment to and a prerequisite for... -
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- Effect of Microalgal Extracts of Tetraselmis suecica against UVB-Induced Photoaging in Human Skin Fibroblasts
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Jo WS, Yang KM, Park HS, Kim GY, Nam BH, Jeong MH, Choi YJ
- KMID: 1432307
- Toxicol Res.
- 2012 Dec;28(4):241-248.
Exposure of cells to ultraviolet B (UVB) radiation can induce production of free radicals and reactive oxygen species (ROS), which damage cellular components. In addition, these agents can stimulate the... -
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- Zearalenone Affects Immune-Related Parameters in Lymphoid Organs and Serum of Rats Vaccinated with Porcine Parvovirus Vaccine
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Choi BK, Cho JH, Jeong SH, Shin HS, Son SW, Yeo YK, Kang HG
- KMID: 1432312
- Toxicol Res.
- 2012 Dec;28(4):279-288.
Rats were administered zearalenone (ZEA) via gavage at dosages of 0, 1, 5, and 30 mg/kg for 36 days. On treatment day 8, inactivated porcine parvovirus vaccine (Vac) was injected... -
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