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A positive feedback loop of heparanase/ syndecan1/nerve growth factor regulates cancer pain progression

Su X, Wang B, Zhou Z, Li Z, Tong S, Chen S, Zhang N, Liu S, Zhang M

Background: The purpose of this research was to assess the role of heparanase (HPSE)/syndecan1 (SDC1)/nerve growth factor (NGF) on cancer pain from melanoma. Methods: The influence of HPSE on the biological...
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Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice

Huang Z, Yu M, Tong S, Jia K, Liu R, Wang H, Li S, Ning Z

Activation of the innate immune system requires recognition of pathogen-associated molecular patterns, such as NOD-like receptors. The NOD-like receptor protein 3 (NLRP3) inflammasome is involved in induction of the pro-inflammatory...
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From DCPD to NTCP: The long journey towards identifying a functional hepatitis B virus receptor

Li J, Tong S

Hepatitis B virus (HBV) is the prototype of hepatotropic DNA viruses (hepadnaviruses) infecting a wide range of human and non-human hosts. Previous studies with duck hepatitis B virus (DHBV) identified...
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