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Molecular biologic research in the thyrotropin releasing hormone

Yang IM

  • KMID: 1686661
  • J Korean Soc Endocrinol.
  • 1991 Sep;6(3):271-275.
No abstract available.
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Effect of Ga2 gene mutation on the Expression of Thyrotropin-Releasing Hormone ( TRH ) Receptor Gene in GH3 Cells

Park SJ, Yang IM, Ryu JH, Chung JH, Jung JC, Ko KC, Kim YS, Choi YK

  • KMID: 1999281
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):357-363.
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Clinical Study on the Effect of TRH in Patients with Prolonged Mild Disturbance of Consciousness

Han DH, Jung HW, Sim BS

  • KMID: 2187409
  • J Korean Neurosurg Soc.
  • 1985 Sep;14(3):519-526.
Authors report the clinical study on the usefulness of thyrotropin-releasing hormone tartrate(TRH-T) in the treatment of mild disturbance of consciousness. 20 patients suffering head trauma, subarachnoid hemorrhage, and intracerebral hemorrhage...
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Reversible Pituitary Dysfunction in a Patient with Cushing's Syndrome due to Adrenal Adenoma

Kong JH, Kim KW, Kim HJ, Nam JS, Park JA, Park JS, Kim CS, Moon BS, Hong SW, Ahn CW, Kim KR

A 45-year-old woman who complained of weight gain and irregular menstruation was diagnosed as having Cushing's syndrome due to a 3 cm sized left adrenal adenoma. She underwent left adrenalectomy,...
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A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis

Park JH, Lee SG, Park EK, Koo DW, Kim BH, Kim IJ, Kim GT

A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the...
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Identification of a de novo mutation (H435Y) in the THRB gene in a Korean patient with resistance to thyroid hormone

Shin JY, Ki CS, Kim JK

The syndrome of resistance to thyroid hormone (RTH) is characterized by reduced tissue sensitivity to thyroid hormone (TH). In the majority of subjects, RTH is caused by mutations in the...
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Neonatal screening and a new cause of congenital central hypothyroidism

Tajima T, Nakamura A, Morikawa S, Ishizu K

Congenital central hypothyroidism (C-CH) is a rare disease in which thyroid hormone deficiency is caused by insufficient thyrotropin (TSH) stimulation of a normally-located thyroid gland. Most patients with C-CH have...
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The Effect of Thyrotropin Releasing Hormone on the Somatosensory Evoked Potentials and the Ultrastructure of Myelinated Nerve Fibers in Injuried Spinal Cord

Lee SM, Lee KC

  • KMID: 2187732
  • J Korean Neurosurg Soc.
  • 1990 Jul;19(7):1033-1043.
The purpose of this study was to determine the effect of treatment with thyrotropin releasing hormone(TRH) on the somatosensory evoked potentials(SSEPs) and ultrastructures of myelinated nerve fibers in injured spinal...
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The Effect of Thyrotropin Releasing Hormone on somatosensory Evoked Potentials in Cats with Spinal Cord Injury

Park CO, Lee KC, Leem JW, Paik KS

  • KMID: 2068312
  • J Korean Neurosurg Soc.
  • 1987 Mar;16(1):255-264.
The therapeutic goal for the spinal injury has been focused on preventing the secondary ischemic changes because of the poor regeneration of human spinal cord. Naloxone, an antagonist of endogenous...
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A Case of Gonadotropin-Producing Pituitary Adenoma

Lee SD, Ha YS, Park CO, Kim Y, Chae KB, Kim JM

  • KMID: 2067968
  • J Korean Neurosurg Soc.
  • 1993 Jun;22(6):770-778.
A 58-year-old male with a pituitary adenoma was investigated and demonstrated to have hypersecretion of both gonadotropins in the basal state. Presenting symptoms included visual disturbance, headache, loss of libido,...
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Hypothalamic Hypopituitarism Caused by Pituitary Stalk Dysgenesis

Lee SJ, Yoon HJ, Cho AR, Um YJ, Park KY, Lim DM, Kim BJ

  • KMID: 2267795
  • Korean J Med.
  • 2013 Oct;85(4):420-424.
Functional defects of the pituitary gland are a rare cause of pubertal delay. The pituitary stalk is an important structure that connects the hypothalamus and pituitary gland. A defect in...
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Subclinical hypothyroidism diagnosed by thyrotropin-releasing hormone stimulation test in infertile women with basal thyroid-stimulating hormone levels of 2.5 to 5.0 mIU/L

Lee YJ, Kim CH, Kwack JY, Ahn JW, Kim SH, Chae HD, Kang BM

OBJECTIVE: To investigate the prevalence of subclinical hypothyroidism (SH) diagnosed by thyrotropin-releasing hormone (TRH) stimulating test in infertile women with basal thyroid-stimulating hormone (TSH) levels of 2.5 to 5.0 mIU/L. METHODS:...
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Discrepancy between in vitro and in vivo effect of Galphas gene mutation on the mRNA expression of TRH receptor

Park S, Yang I, Yim S, Chung J, Jung J, Ko K, Kim Y, Choi Y

  • KMID: 2071530
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):101-108.
We investigated the effect of alpha-subunit of the stimulatory GTP-binding protein (Galphas) gene mutation on the expression of the thyrotropin-releasing hormone (TRH) receptor (TRH-R) gene in GH3 cells and in growth hormone (GH)-secreting...
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Interpretation of puzzling thyroid function tests

Yoon JH, Kang HC

With the generalized use of highly sensitive thyroid stimulating hormone (TSH) and free thyroid hormone assays, most thyroid function tests (TFTs) are straightforward to interpret and confirm the clinical impressions...
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Characterization of Cyclic AMP Response Element (CRE) in the Promoter of the Rat Thyrotropin Releasing Hormone (TRH) Gene

Jung WW, Yang IM, Seo KS, Jung SW

  • KMID: 2461510
  • J Korean Soc Endocrinol.
  • 1994 Sep;9(3):190-199.
We investigated whether the two variant elements of CRE(TGcCGTCA[5'CRE], TGACcTCA[3'CRE]) in the 5'flanking region of the rat TRH gene, which are different from the CRE consensus sequence(5'-TGACGTCA-3') by one base...
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The Effect of Octreotide LAR on GH and TSH Co-Secreting Pituitary Adenoma

Kim NK, Hah YJ, Lee HY, Kim SJ, Kim MK, Park KG, Kim E, Chang H, Kim HS

Growth hormone (GH) and thyroid stimulating hormone (TSH)-secreting pituitary adenomas are very rare and they account for only 0.5% for all pituitary adenomas. These adenomas are usually treated with surgery,...
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The Effects of an Extract of Atractylodes Japonica Rhizome, SKI3246 on Gastrointestinal Motility in Guinea Pigs

Park JJ, Chon NR, Lee YJ, Park H

  • KMID: 2433474
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):352-360.
  • doi: 10.5056/jnm14112
BACKGROUND/AIMS: There are limited therapeutic options available for irritable bowel syndrome with diarrhea (IBS-D). We tested the effects of Atractylodes japonica rhizome, a perennial plant native to North Asia, on...
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Effects of Ramosetron on Gastrointestinal Transit of Guinea Pig

Park YM, Lee YJ, Lee YH, Kim TI, Park H

  • KMID: 2325969
  • J Neurogastroenterol Motil.
  • 2013 Jan;19(1):36-41.
BACKGROUND/AIMS: A selective 5-hydroxytryptamine (5-HT) type 3 receptor antagonist, ramosetron, inhibits stress-induced abnormal defecation in animals and is currently used as a therapeutic drug for irritable bowel syndrome with diarrhea....
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Antenatal Thyrotropin-Releasing Hormone to Prevent Respiratory Distress Syndrome in Preterm

Kim AR, Park SJ, Yoon HS, Kim KS, Won HS, Lee IS, Kim A, Pi SY

  • KMID: 1748173
  • J Korean Pediatr Soc.
  • 1999 Jul;42(7):911-920.
PURPOSE: The purpose of this study was to assess the efficacy of antenatal thyrotropin-releasing hormone(TRH) given to mothers at risk for preterm delivery and assess various neonatal outcomes in infants...
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The role of K+ channels on spontaneous action potential in rat clonal pituitary GH3 cell line

Rhim H, Baek HJ, Ho WK, Earm YE

  • KMID: 1982593
  • Korean J Physiol Pharmacol.
  • 2000 Apr;4(2):81-90.
The types of K+ channel which determine the pattern of spontaneous action potential (SAP) were investigated using whole-cell variation of patch clamp techniques under current- and voltage-clamp recording conditions in rat clonal pituitary...
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