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Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.

Oh SI, Lee MS, Kim CI, Song KY, Park SC

  • KMID: 1093597
  • Exp Mol Med.
  • 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in...
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Iron Supplementation in Experimental Hyperthyroidism: Effects on Oxidative Stress in Skeletal Muscle Tissue

Seymen HO, Civelek S, Seven A, Yigit G, Hatemi H, Burcak G

This study was designed to investigate the effects of iron supplementation on the parameters of oxidative stress in the skeletal muscle tissue of hyperthyroidism induced rats. Hyperthyroidism was found to...
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Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro

Kim JW, Kang KW, Oh GT, Song J, Kim ND, Pak YK

  • KMID: 1081463
  • Exp Mol Med.
  • 2002 May;34(2):137-144.
Cholesterol-rich diet impairs endothelial NO synthase (eNOS) and enhances inducible NOS (iNOS) expression. In this study, we investigated effects of cholesterol on iNOS expression in high-fat-fed rat models, HepG2 and...
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Effects of glutamate on dehydroascorbate uptake and Its enhanced vulnerability to the peroxidation in cerebral cortical slices

Song JH, Shin SH, Chung IM

  • KMID: 1121095
  • Exp Mol Med.
  • 2002 Dec;34(6):419-425.
Pro-oxidant properties of ascorbate have been studied with uses of brain tissues and neuronal cells. Here we address potential mechanism of ascorbate coupling with glutamate to generate oxidative stress,...
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Rapid uptake of oxidized ascorbate induces loss of cellular glutathione and oxidative stress in liver slices

Song JH, Simons C, Cao L, Shin SH, Hong M, Chung IM

  • KMID: 1097253
  • Exp Mol Med.
  • 2003 Apr;35(2):67-75.
The observation that ascorbate known to retain pro-oxidant properties induces cell death in a number of immortal cell lines, led us to examine its mechanism and whether it is involved...
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Oxidation-dependent effects of oxidized LDL: proliferation or cell death

Han CY, Kim Pak YM

  • KMID: 1029922
  • Exp Mol Med.
  • 1999 Dec;31(4):165-173.
Oxidized low-density lipoprotein (oxLDL) induces a wide range of cellular responses to produce atherosclerotic lesion, but key factors determining the response are not understood. In this study, purified...
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