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Transient Myeloproliferative Disorder with Mosaic Down Syndrome: A Case Report

Kim SE, Kim SH, Kim MY, Lee JN, Lee SY

  • KMID: 2083419
  • Korean J Hematol.
  • 2000 May;35(2):179-183.
Individuals with Down syndrome have a high incidence of hematologic diseases such as transient myeloproliferative disorder (TMD) and acute leukemia comparing to the normal children. TMD usually undergoes complete recovery...
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A Case of Primary Bone Marrow Lymphoma Secondary to Aplastic Anemia

Moon Y, Lee A, Kim B, Eom H, Han C

  • KMID: 2083417
  • Korean J Hematol.
  • 2000 May;35(2):171-173.
Primary bone marrow lymphomas are infrequent. We report a case of primary bone marrow T-cell lymphoma in a 33-year old patient who has been treated as a hypocellular marrow. There...
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An ALL Case with Trichosporon beigelii Pneumonia Developed during Severe Pancytopenic Period after Salvage Chemotherapy

Jung JT, Baik JH, Kim DH, Kwak DS, Park SH, Sohn SK, Suh JS, Lee KB

  • KMID: 2083415
  • Korean J Hematol.
  • 2000 May;35(2):162-166.
Trichosporon beigelii belongs to the family of Cryptococcaceae. T. beigelii is a rare causative agent of invasive pneumonia in immunocompromised patients. T. beigelii pneumonia is characterized by persistent fever unresponsive...
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A Case of Wilson's Disease Presenting and Flare-up as Acute Hemolytic Anemia and Fulminant Hepatitis Features

Kim JY, Na KS, Kim SH, Kim IS

  • KMID: 2083416
  • Korean J Hematol.
  • 2000 May;35(2):167-170.
Wilson's Disease is a rare familial disorder of abnomalities in hepatic copper metabolism usually presenting with neuropsychiatric or hepatic manifestation. Hemolytic anemia is known as one of its initial clinical...
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A Case of Myeloperoxidase Deficiency Diagnosed with the Neutrophil Function Test

Choi SJ, Park CJ, Chi HS, Hong SJ

  • KMID: 2083420
  • Korean J Hematol.
  • 2000 May;35(2):184-188.
Myeloperoxidase (MPO), an iron-containing heme protein localized in the azurophilic granules of neutrophils and in the lysosomes of monocytes, is involved in the killing of several micro-organisms and foreign cells,...
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A Case of Acute Promyelocytic Leukemia with 46, XX, del(5)(q23)/47, XX, del(5)(q23), +8 but Without (15;17) Translocation

Oh SJ, Kim H, Ahn MJ, Kim IS, Jeong TJ, Choi IY, Chae JD, Lee WS, Cho YH, Lee YY

  • KMID: 2083418
  • Korean J Hematol.
  • 2000 May;35(2):174-178.
Acute promyelocytic leukemia (APL/AML- M3) is a distinct subtype of acute myelogenous leukemia, which is characterized by unique morphologic, cytogenetic, molecular, and clinical features. In almost all APL patients, a...
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Mutation Analysis of PIG-A Gene in Korean Patients with Paroxysmal Nocturnal Hemoglobinuria

Yoon JH, Cho HI, Park SS, Chang YH

  • KMID: 2083413
  • Korean J Hematol.
  • 2000 May;35(2):143-149.
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is caused by deficient biosynthesis of the glycosylphosphatidylinositol (GPI) anchor in hemopoietic stem cells. Mutation of phosphatidyl inositol glycan class A (PIG-A) gene, an X-linked...
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A Case of Juvenile Myelomonocytic Leukemia in a Six Months Old Infant

Chang EA, Kim MK, Lim YA, Hyun BH, Kim SW, Park KH, Hong J

  • KMID: 2083421
  • Korean J Hematol.
  • 2000 May;35(2):189-194.
Myelodysplastic syndrome (MDS) in childhood is a rare hematologic malignancy and its classification has been the subject of some controversy. Cases of pediatric MDS are subdivided into those with features...
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Change of Erythropoiesis and Serum Transferrin Receptor Levels with Gestational Age in Healthy Pregnant Women

Choi JW, Im MW, Pai SH

  • KMID: 2083412
  • Korean J Hematol.
  • 2000 May;35(2):134-142.
BACKGROUND: To investigate the change of iron dynamics, erythropoiesis, and serum transferrin receptor (sTfR) concentration during pregnancy, we measured the reticulocyte subpopulations, reticulocyte maturity index (RMI) and sTfR concentration in...
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Therapeutic Effect and Prognostic Analysis of Induction Chemotherapy with Idarubicin/BH-AC in Acute Myelogenous Leukemia

Lee JJ, Chung IJ, Yang DH, Cho SH, Yang TY, Park HC, Park MR, Kim HJ

  • KMID: 2083409
  • Korean J Hematol.
  • 2000 May;35(2):109-116.
BACKGROUND: We have analyzed the outcome and prognostic factors for 61 patients with acute myelogenous leukemia (AML) who were treated with idarubicin(IDA)/N 4-behenoyl- 1-beta-D-arabinofuranosylcytosine(BH-AC) regimen at Chonnam National University Hospital...
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Establishment of Multi-Drug Resistance Functional Assay and Correlation of Multi-Drug Resistance Activity and Chemotherapeutic Outcomes in Patients with Acute Leukemia

Park CJ, Kim MC, Han TJ, Seo EJ, Chi HS, Lee JH, Suh C, Lee KH, Kim WK

  • KMID: 2083408
  • Korean J Hematol.
  • 2000 May;35(2):97-108.
BACKGROUND: Multi-drug resistance (MDR) is one of the most important obstacles in the chemotherapy of acute leukemia, so the modulators of MDR have been developed and tried. METHODS: We measured...
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The Frequency and Clinical Significance of Multidrug Resistance-1 (MDR-1) Gene Expression in Acute Myeloid Leukemia

Baek JH, Park SW, Kim DH, Jung JT, Kwak DS, Park SH, Sohn SK, Suh JS, Lee KS, Lee JT, Lee KB

  • KMID: 2083410
  • Korean J Hematol.
  • 2000 May;35(2):117-125.
BACKGROUND: The expression of the multidrug resistance-1 (MDR-1) gene which encodes p-glycoprotein, is recognized as a biological mechanism possibly contributing to treatment failure in patients with acute myeloid leukemia (AML)....
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Correlation between the Expression Levels of Transforming Growth Factor-beta (TGF-beta) Receptors and Responsiveness to TGF-beta1-Induced Growth Inhibitory Effects in Leukemic Cell Lines

Jeon JH, Park BK

  • KMID: 2083414
  • Korean J Hematol.
  • 2000 May;35(2):150-161.
BACKGROUND: Defects in TGF-beta receptors have been found in a variety of malignant cells, we therefore investigated whether these defects could be also demonstrated in leukemic cells. In addition, we...
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Establishment of Adherent Cell Layers from Human Cord Blood CD34+ Cells During Long-Term Liquid Culture Using TPO, FL, and G-CSF

Yoo ES, Seong CM

  • KMID: 2083411
  • Korean J Hematol.
  • 2000 May;35(2):126-133.
BACKGROUND: The stromal cells, which one part of the microenvironment, including adipocyte, fibroblasts, endothelial cells, macrophage and smooth muscle cells provide a suitable environment for self-renewal, proliferation and differentiation of...
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