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Primary Adenocarcinoma of the Minor Duodenal Papilla

Wakatsuki , Irisawa A, Takagi T, Koyama Y, Hoshi S, Takenoshita S, Abe M, Ohira H

A 70-year-old man was admitted to our institution due to aggravation of blood-sugar level control and because an abdominal CT showed dilatation of the main pancreatic duct. Upper gastrointestinal endoscopy...
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Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice

Yamanaka H, Kadomatsu , Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K

Isolates of 24 enterococci, 5 Enterococcus casseliflavus and 19 Enterococcus gallinarum, possessing vanC genes and showing low-level resistance to vancomycin were obtained from mice from commercial mouse breeding companies. Since...
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Impact of preoperative proteinuria on renal functional outcomes after open partial nephrectomy in patients with a solitary kidney

Tachibana , Kondo T, Takagi T, Okumi M, Tanabe K

PURPOSE: To assess the impact of proteinuria on postoperative renal function after open partial nephrectomy (OPN) in patients with a solitary kidney and analyze predictive factors for developing chronic kidney...
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A multicenter comparative study of endoscopic ultrasound-guided fine-needle biopsy using a Franseen needle versus conventional endoscopic ultrasound-guided fine-needle aspiration to evaluate microsatellite instability in patients with unresectable pancreatic cancer

Takagi T, Sugimoto M, Imamura H, Takahata Y, Nakajima Y, Suzuki R, Konno N, Asama H, Sato Y, Irie H, Nakamura J, Takasumi M, Hashimoto M, Kato T, Kobashi R, Hashimoto Y, Shibukawa G, Marubashi S, Hikichi T, Ohira H

Background/Aims: Immune checkpoint blockade has recently been reported to be effective in treating microsatellite instability (MSI)-high tumors. Therefore, sufficient sampling of histological specimens is necessary in cases of unresectable pancreatic...
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Association Between the Cool Temperature-dependent Suppression of Colonic Peristalsis and Transient Receptor Potential Melastatin 8 Activation in Both a Randomized Clinical Trial and an Animal Model

Sugino S, Inoue K, Kobayashi R, Hirose R, Doi T, Harusato A, Dohi O, Yoshida N, Uchiyama K, Ishikawa T, Takagi T, Yasuda H, Konishi H, Hirai Y, Mizushima K, Naito Y, Tsuji T, Okuda T, Kagawa K, Tominaga M, Itoh Y

  • KMID: 2534327
  • J Neurogastroenterol Motil.
  • 2022 Oct;28(4):693-705.
  • doi: 10.5056/jnm21198
Background/Aims Several studies have assessed the effect of cool temperature on colonic peristalsis. Transient receptor potential melastatin 8 (TRPM8) is a temperature-sensitive ion channel activated by mild cooling expressed in the...
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