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Bone Regeneration with MMP sensitive hyaluronic acid-based hydrogel, rhBMP-2 and nanoparticles in rat calvarial critical size defect(CSD) model

Park JC, Yu SB, Chung YI, Tae GY, Kim JJ, Park YD, Jahng JW, Lee JH

  • KMID: 2398980
  • J Korean Assoc Oral Maxillofac Surg.
  • 2009 Jun;35(3):137-145.
As an efficient controlled release system for rhBMP-2, a functional nanoparticle-hydrogel complex, incorporated with matrix metalloproteinase( MMP) sensitive peptide cross-linker, was developed and used as a bone transplant. In vivo...
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