- Treadmill exercise prevents diabetes-induced increases in lipid peroxidation and decreases in Cu,Zn-superoxide dismutase levels in the hippocampus of Zucker diabetic fatty rats
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Kim JW, Chae J, Nam SM, Kim YN, Yoo DY, Choi JH, Jung HY, Song W, Hwang IK, Seong JK, Yoon YS
- KMID: 2160815
- J Vet Sci.
- 2015 Mar;16(1):11-16.
- doi: 10.4142/jvs.2015.16.1.11
In the present study, we investigated the effects of treadmill exercise on lipid peroxidation and Cu,Zn-superoxide dismutase (SOD1) levels in the hippocampus of Zucker diabetic fatty (ZDF) rats and lean... -
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- Intracellular amyloid beta interacts with SOD1 and impairs the enzymatic activity of SOD1: implications for the pathogenesis of amyotrophic lateral sclerosis
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Yoon EJ, Park HJ, Kim GY, Cho H, Choi JH, Park HY, Jang JY, Rhim H, Kang S
- KMID: 756204
- Exp Mol Med.
- 2009 Sep;41(9):611-617.
- doi: 10.3858/emm.2009.41.9.067
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the degeneration of motor neurons. Mutations in Cu/Zn superoxide dismutase (SOD1), including G93A, were reportedly linked to familial ALS. SOD1... -
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- Effects of Antioxidant on Reduction of Hindlimb Muscle Atrophy Induced by Cisplatin in Rats
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Kim JI, Choe MA
- KMID: 1791866
- J Korean Acad Nurs.
- 2014 Aug;44(4):371-380.
- doi: 10.4040/jkan.2014.44.4.371
PURPOSE: The purpose of this study was to examine the effects of Cu/Zn SOD on reduction of hindlimb muscular atrophy induced by cisplatin in rats. METHODS: Forty-two rats were assigned to... -
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- Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes
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Song HY, Ju SM, Lee JA, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J
- KMID: 1091072
- Exp Mol Med.
- 2007 Dec;39(6):778-786.
HIV-1 Tat is considered to be one of key players to facilitate monocyte entry into the CNS, which is characteristic feature of AIDS-related encephalitis and dementia. This study was performed... -
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- Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
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Guo YS, Wu DX, Wu HR, Wu SY, Yang C, Li B, Bu H, Zhang YS, Li CY
- KMID: 1123461
- Exp Mol Med.
- 2009 Mar;41(3):140-150.
- doi: 10.3858/emm.2009.41.3.017
A subset of patients of amyotrophic lateral sclerosis (ALS) present with mutation of Cu/Zn superoxide dismutase 1 (SOD1), and such mutants caused an ALS-like disorder when expressed in rodents. These... -
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- Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes
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Kim SJ, Hur JH, Park C, Kim HJ, Oh GS, Lee JN, Yoo SJ, Choe SK, So HS, Lim DJ, Moon SK, Park R
- KMID: 2155407
- Exp Mol Med.
- 2015 Feb;47(2):e142.
- doi: 10.1038/emm.2014.112
Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats... -
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- Over-expression of extracellular superoxide dismutase in mouse synovial tissue attenuates the inflammatory arthritis
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Yu DH, Yi JK, Yuh HS, Park SJ, Kim HJ, Bae KB, Ji YR, Kim NR, Park SJ, Kim DH, Kim SH, Kim MO, Lee JW, Ryoo ZY
- KMID: 1389732
- Exp Mol Med.
- 2012 Sep;44(9):529-535.
Oxidative stress such as reactive oxygen species (ROS) within the inflamed joint have been indicated as being involved as inflammatory mediators in the induction of arthritis. Correlations between extracellular-superoxide dismutase... -
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- Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice
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Park S, Kim HT, Yun S, Kim IS, Lee J, Lee IS, Park KI
- KMID: 1058023
- Exp Mol Med.
- 2009 Jul;41(7):487-500.
- doi: 10.3858/emm.2009.41.7.054
Neural progenitor cells (NPs) have shown several promising benefits for the treatment of neurological disorders. To evaluate the therapeutic potential of human neural progenitor cells (hNPs) in amyotrophic lateral sclerosis... -
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