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Accurate transfer of bimaxillary orthognathic surgical plans using computer-aided intraoperative navigation

Chen C, Sun N, Jiang C, Liu Y, Sun J

Objective: To examine the accuracy of computer-aided intraoperative navigation (Ci-Navi) in bimaxillary orthognathic surgery by comparing preoperative planning and postoperative outcome. Methods: The study comprised 45 patients with congenital dentomaxillofacial deformities...
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Seroprevalence of Toxoplasma gondii Infection in Police Dogs in Shenyang, Northeastern China

Liu CW, Yang N, He JB, Mu MY, Yang M, Sun N, Li HK

  • KMID: 1792152
  • Korean J Parasitol.
  • 2013 Oct;51(5):579-581.
In recent years, worldwide surveys of Toxoplasma gondii infection in dogs have been reported. However, only limited surveys of T. gondii infection in police dogs have been available, including China....
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Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Min C, Zhang X, Zheng M, Sun N, Acharya S, Zhang X, Kim KM

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which...
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C-Reactive Protein Gene Variants in Depressive Symptoms & Antidepressants Efficacy

Li X, Sun N, Yang C, Liu Z, Li X, Zhang K

OBJECTIVE: Although the pathogenesis of depression remains unclear, C-reactive protein (CRP) levels are commonly elevated in depressed patients. Thus, CRP single-nucleotide polymorphisms (SNPs) that influence CRP levels may be associated...
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Role of Helix 8 in Dopamine Receptor Signaling

Yang HS, Sun N, Zhao X, Kim HR, Park HJ, Kim KM, Chung KY

G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been...
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Metformin alleviates chronic obstructive pulmonary disease and cigarette smoke extract-induced glucocorticoid resistance by activating the nuclear factor E2-related factor 2/heme oxygenase-1 signaling pathway

Tao F, Zhou Y, Wang M, Wang C, Zhu W, Han Z, Sun N, Wang D

Chronic obstructive pulmonary disease (COPD) is an important healthcare problem worldwide. Often, glucocorticoid (GC) resistance develops during COPD treatment. As a classic hypoglycemic drug, metformin (MET) can be used as...
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The Protective Role of TLR3 and TLR9 Ligands in Human Pharyngeal Epithelial Cells Infected with Influenza A Virus

Han Y, Bo ZJ, Xu MY, Sun N, Liu DH

In this study we aim to extensively investigate the anti-influenza virus immune responses in human pharyngeal epithelial cell line (Hep-2) and evaluate the protective role of Toll-like receptor (TLR) ligands...
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Brain Imaging Study on the Pathogenesis of Depression & Therapeutic Effect of Selective Serotonin Reuptake Inhibitors

Meng Q, Zhang A, Cao X, Sun N, Li X, Zhang Y, Wang Y

Objective Predefining the most effective treatment for patients with depressive disorders remains a problem. We will examine the differential brain regions of gray matter (GM) in major depressive disorder (MDD)...
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