- Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis
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Kim H, Hur M, Struck J, Bergmann A, Di Somma S
- KMID: 2450968
- Ann Lab Med.
- 2019 Sep;39(5):454-463.
- doi: 10.3343/alm.2019.39.5.454
BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis. We explored whether bio-ADM concentration... -
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- Proenkephalin Predicts Organ Failure, Renal Replacement Therapy, and Mortality in Patients With Sepsis
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Kim H, Hur M, Struck J, Bergmann A, Somma SD, on behalf of GREAT Network
- KMID: 2507792
- Ann Lab Med.
- 2020 Nov;40(6):466-473.
- doi: 10.3343/alm.2020.40.6.466
Background: Kidney failure occurs frequently and is associated with high mortality during sepsis. Proenkephalin (PENK) is an emerging biomarker of kidney function. We explored whether PENK levels could predict severity,... -
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- Proenkephalin, Neutrophil Gelatinase-Associated Lipocalin, and Estimated Glomerular Filtration Rates in Patients With Sepsis
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Kim H, Hur M, Lee S, Marino R, Magrini L, Cardelli P, Struck J, Bergmann A, Hartmann O, Di Somma S, GREAT Network
- KMID: 2383914
- Ann Lab Med.
- 2017 Sep;37(5):388-397.
- doi: 10.3343/alm.2017.37.5.388
BACKGROUND: Proenkephalin (PENK) has been suggested as a novel biomarker for kidney function. We investigated the diagnostic and prognostic utility of plasma PENK in comparison with neutrophil gelatinase-associated lipocalin (NGAL)... -
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