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Cell Death Mechanisms in Esophageal Squamous Cell Carcinoma Induced by Vesicular Stomatitis Virus Matrix Protein

Douzandegan Y, Tahamtan A, Gray Z, Nikoo HR, Tabarraei , Moradi A

OBJECTIVES: Vesicular stomatitis virus (VSV) is under development as an oncolytic virus due to its preferential replication in cancer cells and oncolytic activity, however the viral components responsible have not...
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The Effects of Oral Cryotherapy on Oral Mucositis, Reactive Oxygen Series, Inflammatory Cytokines, and Oral Comfort in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial

Shin N, Kang Y

PURPOSE: The purpose of this study was to examine the effects of oral cryotherapy on oral mucositis, reactive oxygen series, inflammatory cytokines, and oral comfort in patients undergoing chemotherapy for...
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Oral Health Status and Oral Health-related Quality of Life According to Presence or Absence of Mucositis in Head and Neck Cancer Patients

Jung YS, Park EY, Sohn HO

BACKGROUND: Oral mucositis during radiotherapy which is harmful to the patients with head and neck is suggested to be related to the oral hygiene and health. Therefore, we evaluated the...
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Clinical Manifestations of PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis) Syndrome from a Single Center

Shin M, Choi EH, Han MS

PURPOSE: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is a leading cause of periodic fever in children. This study describes the clinical characteristics of PFAPA syndrome in patients...
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Staged lower lip reconstruction following gangrenous stomatitis in an immunosuppressed patient

Jin HB, Yang JY, Kim KS, Kim SH, Choe J, Chung JH

A 70-year-old male with a history of diabetes mellitus, hypertension, and coronary stent insertion visited our hospital 7 days after biting his lower lip. Swelling and inflammation had worsened despite...
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Effect of Oral Cryotherapy for Reducing Oral Mucositis in Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-analysis

Park SH, Han SH

PURPOSE: This systematic review and meta-analysis provided scientific evidence for oral cryotherapy as a nursing intervention for the prevention of Oral Mucositis (OM) associated with Hematopoietic Stem Cell Transplantation (HSCT). METHODS:...
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Phase 1 Studies of Poziotinib, an Irreversible Pan-HER Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors

Kim TM, Lee KW, Oh DY, Lee JS, Im SA, Kim DW, Han SW, Kim YJ, Kim TY, Kim JH, Han H, Kim WH, Bang YJ

PURPOSE: Poziotinib, a pan-human epidermal growth factor receptor 2 (HER) tyrosine kinase inhibitor, has shown potent activity againstwild type of epidermal growth factorreceptor(EGFR) family kinases including EGFR, HER2, and HER4...
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Radiotherapy in the Region of the Head and Neck and the Consequential Changes in Normal Tissues

Han TJ

Radiotherapy is a crucial non-surgical modality for head and neck cancer. With increasing radiation dose, the possibility of tumor control increases but the probability of toxicity to the surrounding normal...
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Phase II Study of Induction Chemotherapy with Docetaxel, Capecitabine, and Cisplatin Plus Bevacizumab for Initially Unresectable Gastric Cancer with Invasion of Adjacent Organs or Paraaortic Lymph Node Metastasis

Kim JH, Park SR, Ryu MH, Ryoo BY, Kim KP, Kim BS, Yoo MW, Yook JH, Kim BS, Kim J, Byeon SJ, Kang YK

PURPOSE: The purpose of this study was to evaluate the efficacy and safety of induction chemotherapy with docetaxel, capecitabine, and cisplatin (DXP) plus bevacizumab (BEV) on initially unresectable locally advanced...
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Denture wearers' recognition for their oral health status, denture cleansing methods, and insurance health system

Kim S, Kim SK, Noh K, Ahn SJ, Baik SH, Kim JH, Yoo DK, Kim KR, Kwon KR

PURPOSE: The aim of the present investigation was to understand the incidence, prevalence of denture stomatitis in denture wearers, who were over 60 years old, and use the results for...
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Topotecan-Vincristine-Doxorubicin in Stage 4 High-Risk Neuroblastoma Patients Failing to Achieve a Complete Metastatic Response to Rapid COJEC: A SIOPEN Study

Amoroso L, Erminio G, Makin G, Pearson AD, Brock P, Valteau-Couanet D, Castel V, Pasquet M, Laureys G, Thomas C, Luksch R, Ladenstein R, Haupt R, Garaventa , SIOPEN Group

PURPOSE: Metastatic response to induction therapy for high-risk neuroblastoma is a prognostic factor. In the International Society of Paediatric Oncology Europe Neuroblastoma (SIOPEN) HR-NBL-1 protocol, only patients with metastatic complete...
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Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study

Kim HJ, Kim Y, Lee SJ, Lee J, Park SH

OBJECTIVE: In the treatment of metastatic soft tissue sarcoma (STS), pazopanib is considered a standard treatment after failure of chemotherapy. We retrospectively investigated outcomes of pazopanib in patients with metastatic...
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Screening of Antibiotics that Selectively Inhibit a Bacterial Species Associated with a Recurrent Aphthous Stomatitis Risk

Lee A, Kim Y, Choi Y

Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder for which no curative treatment is available. We previously reported that decreased Streptococcus salivarius and increased Acinetobacter johnsonii on the...
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Behçet's disease with multiple splenic abscesses in a child

Lim KI, Yang DH, Ryoo E

We report the case of a 5-year-old male patient with multiple aseptic splenic abscesses associated with Behçet's disease. The patient visited Gachon University Gil Hospital with fever, abdominal pain, and...
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Treatment and outcomes: medical and surgical treatment for intestinal Behçet's disease

Hisamatsu , Hayashida

Behçet's disease (BD) is a chronic relapsing disease involving multiple organ systems. BD is characterized clinically by oral and genital aphthae, cutaneous lesions, and ophthalmological, neurological, and/or gastrointestinal manifestations. It...
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Elimination of unplanned treatment breaks and dose reductions caused by mucositis: Positive implications for survival outcomes and cost reductions using high potency polymerized cross-linked sucralfate in 55 patients undergoing radiation for head and neck cancer with and without chemotherapy

McCullough RW

PURPOSE: Annually 27,855 patients in Korea develop treatment-induced mucositis nearly doubling the cost of cancer care. It is an emergency medical condition causing unplanned treatment breaks in 4,998 patients. The...
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A Case of Refractory Oral Aphthous Ulcer Successfully Treated with Adalimumab

Kim J, Song MJ, Jeong HJ, Cho SK, Sung YK

Oral aphthous ulcer is a common lesion characterized by loss of dermal tissue of various shapes in many diseases. It is not serious, but may affect quality of life through...
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Effect of Hippophae rhamnoides Extract on Oxidative Oropharyngeal Mucosal Damage Induced in Rats Using Methotrexate

Erhan E, Terzi S, Celiker M, Yarali O, Cankaya M, Cimen FK, Malkoc I, Suleyman B

OBJECTIVES: The objective of this study is to investigate and evaluate the effect of Hippophae rhamnoides extract (HRE) on oropharyngeal mucositis induced in rats with methotrexate (MTX) through biochemical, gene...
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The Effects of Flash Animation Facilitated Oral Self Care Education on the Incidence of Oral Mucositis and Performance of Self-Care in Pediatric Cancer Patients Undergoing Chemotherapy

Kim YH, Lee H, Jung MJ, Jung H

PURPOSE: In this study, we aimed to investigate the effects of oral self-care education on the oral mucositis and oral self-care performance in pediatric cancer patients undergoing chemotherapy. METHODS: We conducted...
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Stevens-Johnson syndrome and abuse of anabolic steroids

Cocca S, Viviano M

Stevens-Johnson syndrome (SJS) is characterized by mucocutaneous tenderness and typical hemorrhagic erosions, erythema and epidermal detachment presenting as blisters and areas of denuded skin. SJS is often observed after drug...
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