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Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice

Noh JY, Han DH, Kim MH, Ko IG, Kim SE, Park N, Choe HK, Kim KH, Kim K, Kim CJ, Cho S

Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and...
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Epidural Dexamethasone Decreased Inflammatory Hyperalgesia and Spinal cPLA2 Expression in a Rat Formalin Test

Min SH, Soh JS, Park JY, Choi SU, Lee HW, Lee JJ, Kim JH

PURPOSE: The aim of this study was to investigate the effect of epidural dexamethasone on analgesia and cytosolic phospholipase A2 (cPLA2) expression in the spinal cord in a rat formalin...
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Snapshot of degenerative aging of porcine intervertebral disc: a model to unravel the molecular mechanisms

Cho H, Park SH, Lee S, Kang M, Hasty KA, Kim SJ

Larger animal models, such as porcine, have been validated as appropriate models of the human disc with respect to biomechanics and biochemistry. They are advantageous for research as the models...
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Roles of Adenosine and Serotonin Receptors on the Antinociception of Sildenafil in the Spinal Cord of Rats

Lee HG, Kim WM, Park CH, Yoon MH

PURPOSE: The phosphodiesterase 5 inhibitor sildenafil has antinociceptive effects, mediated by an increase in cGMP. This study examined the role of spinal adenosine and serotonin receptors played in the antinociceptive...
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Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis

Moon C, Shin T

  • KMID: 1093622
  • J Vet Sci.
  • 2004 Dec;5(4):289-293.
To investigate the pattern of expression of osteopontin (OPN) in tissues of the central nervous system (CNS) responding to peripheral immunological stimulation, the expression of OPN was studied in the...
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Effects of MK-801 and Morphine on Spinal C-Fos Expression during the Development of Neuropathic Pain

Lee YW, Park KA, Lee WT

The purpose of this study was to investigate the expression of c-fos in the spinal cord during the development of allodynia, induced by peripheral nerve injury. Following tight ligation of...
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Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis

Moon CJ, Lee YD, Shin TK

  • KMID: 1097344
  • J Vet Sci.
  • 2002 Dec;3(4):279-283.
We examined the localization of the anti-apoptotic molecule Bcl-2 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that Bcl-2 was constitutively expressed...
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