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BACKGROUND: Our previous studies suggested that the reactive oxygen radical may be involved in hyperactivation of human sperm, in that superoxide anion promotes, and hydrogen peroxide inhibits, hyperactivation and acrosome...
Plasma membrane hyperpolarization associated with activation of Ca²âº-activated K⺠channels plays an important role in sperm capacitation during fertilization. Although Slo3 (slowpoke homologue 3), together with the auxiliary γ2-subunit, LRRC52...
Oocytes retrieval, in vitro maturation (IVM) and fertilization (IVF) efficiency are inevitable steps towards in vitro production of embryos. In the present study, these parameters were investigated in the ovaries...
Sperm function and male fertility are closely related to pH dependent K⺠current (KSper) in human sperm, which is most likely composed of Slo3 and its auxiliary subunit leucine-rich repeat-containing...