- Botulinum Toxin A Ameliorates Neuroinflammation in the MPTP and 6-OHDA-Induced Parkinson’s Disease Models
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Ham HJ, Yeo IJ, Jeon SH, Lim JH, Yoo SS, Son DJ, Jang SS, Lee H, Shin SJ, Han SB, Yun JS, Hong JT
- KMID: 2524151
- Biomol Ther.
- 2022 Jan;30(1):90-97.
- doi: 10.4062/biomolther.2021.077
Recently, increasing evidence suggests that neuroinflammation may be a critical factor in the development of Parkinson’s disease (PD) in addition to the ratio of acetylcholine/dopamine because dopaminergic neurons are particularly... -
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- Development of Enzyme Linked Immunosorbent Assay for Erythropoietin
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Kim KH, Shim JH, Cho MC, Kang JW, Yoon HE, Yoon DY, Kim JW, Son DJ, Lee JW, Jeong ES, Hong JT, Moon DC
- KMID: 2238885
- Korean J Lab Med.
- 2006 Jun;26(3):185-191.
- doi: 10.3343/kjlm.2006.26.3.185
BACKGROUND: The aim of our study was to optimize and establish erythropoietin (EPO) enzyme linked immunosorbent assay (ELISA) system. METHODS: We prepared several monoclonal and polyclonal antibodies specific to human-EPO. The... -
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- Effect of Ixeris dentata Nakai Extract on Nitric Oxide Production and Prostaglandin E2 Generation in LPS-stimulated RAW264.7 Cells
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Jung YY, Hong JT, Han SB, Park YH, Son DJ
- KMID: 2132707
- Immune Netw.
- 2015 Dec;15(6):325-330.
- doi: 10.4110/in.2015.15.6.325
Inflammation is the basis of severe acute and chronic diseases. This study investigated the anti-inflammatory property of a crude methanol extract (MeOH-ex) and the solvent fractions of Ixeris dentata Nakai... -
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- Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin
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Jeon SH, Lee YS, Yeo IJ, Lee HP, Yoon J, Son DJ, Han SB, Hong JT
- KMID: 2518347
- Immune Netw.
- 2021 Jun;21(3):e22.
- doi: 10.4110/in.2021.21.e22
Chitinase-3-like-1 (CHI3L1) is known to induce inflammation in the progression of allergic diseases. Previous our studies revealed that 2-({3-[2-(1-cyclohexen-1-yl)ethyl]-6,7-dimethoxy-4-oxo-3,4-dihydro-2-quinazolinyl}sulfanyl)-N-(4-ethylphenyl)butanamide (K284-6111; K284), the CHI3L1 inhibiting compound, has the anti-inflammatory effect on... -
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- What Are the Clinical Features and Etiology of Eosinophilic Liver Infiltration?
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Sim DW, Son DJ, Cho E, Choi SK, Shin SS, Jun CH
- KMID: 2446803
- Gut Liver.
- 2019 Mar;13(2):183-190.
- doi: 10.5009/gnl18266
BACKGROUND/AIMS: Although eosinophilic liver infiltration (ELI) is not rare, few data exist regarding its clinical characteristics and etiology. Therefore, we evaluated these aspects to better understand the clinical implications of... -
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- Inhibitory Effect of Carnosol on Phthalic Anhydride-Induced Atopic Dermatitis via Inhibition of STAT3
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Lee DY, Hwang CJ, Choi JY, Park MH, Song MJ, Oh KW, Son DJ, Lee SH, Han SB, Hong JT
- KMID: 2389386
- Biomol Ther.
- 2017 Sep;25(5):535-544.
- doi: 10.4062/biomolther.2017.006
Carnosol is a phenolic antioxidant present in rosemary (Rosmarinus officinalis). It is known for anti-inflammatory effects, analgesic activity and anti-cancer effects. However, no study has been dedicated yet to its... -
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- Risk Factors and On-site Rescue Treatments for Endoscopic Variceal Ligation Failure
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Kim DH, Cho E, Jun CH, Son DJ, Lee MJ, Park CH, Cho SB, Park SY, Kim HS, Choi SK, Rew JS
- KMID: 2424110
- Korean J Gastroenterol.
- 2018 Oct;72(4):188-196.
- doi: 10.4166/kjg.2018.72.4.188
BACKGROUND/AIMS: The success rate of endoscopic variceal ligation (EVL) is about 85–94%. There is only a few studies attempting to determine the cause of EVL failure, and to date, on-site... -
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- Endoscopic Ultrasonographic Characteristics of Gastric Schwannoma Distinguished from Gastrointestinal Stromal Tumor
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Park HC, Son DJ, Oh HH, Oak CY, Kim MY, Chung CY, Myung DS, Jong-Sun J, Cho SB, Lee WS, Joo YE
- KMID: 2373176
- Korean J Gastroenterol.
- 2015 Jan;65(1):21-26.
- doi: 10.4166/kjg.2015.65.1.21
BACKGROUND/AIMS: Gastric schwannoma (GS), a rare neurogenic mesenchymal tumor, is usually benign, slow-growing, and asymptomatic. However, GS is often misdiagnosed as gastrointestinal stromal tumors (GIST) on endoscopic and radiological examinations.... -
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