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Melatonin in Psychiatric Disorders

Lee JS, Kim SG, Kim JH, Jung WY, Park JH

The secretion of melatonin exhibits a circadian rhythm entrained with the sleep-wake cycle. An alteration of this secretory rhythm has been found in various psychiatric disorders. This review summarizes the...
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The Effect of Insomnia Severity on Daytime Sleepiness in Obstructive Sleep Apnea Syndrome

Nam JW, Shin BH, Shin HS, Park M

OBJECTIVES: Whether daytime sleepiness is proportional to the severity of sleep apnea in obstructive sleep apnea syndrome (OSAS) is controversial. In this study we investigated how insomnia severity affects the...
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A Case of Rapidly Developed Obesity Hypoventilation Syndrome in a Patient with Kyphoscoliosis

Kim MY, Jeong JS, Jang YN, Go SE, Lee SH, Moon HS, Kang HH

Obesity hypoventilation syndrome (OHS) is characterized by severe obesity, excessive daytime sleepiness, hypoxemia and hypercapnea. Because OHS mimics pulmonary hypertension or cor pulmonale, clinicians should recognize and treat this syndrome...
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Restless Legs Syndrome in Children and Adolescents with Type 1 Diabetes

Yang WS, Yoo JH, Cheon SM, Kim SH, Choe BM, Kim WJ, Bang YR, Park JH

OBJECTIVES: Restless legs syndrome (RLS) is a common sleep disorder in adults with diabetes. This study investigated the frequency of RLS and clinical correlations in children and adolescents with type...
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Association between Antipsychotic-Induced Restless Legs Syndrome and Glutathione S-Transferase Gst-M1, Gst-T1 and Gst-P1 Gene Polymorphisms

Kang SG, Park YM, Kim L, Lee HJ

OBJECTIVES: The pathophysiology of restless legs syndrome (RLS) has not been fully elucidated. Oxidative stress might play a role in the development of RLS and other antipsychotic-induced side effects such...
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