- Molecular Genetic Synthesis and Clinical Applications of Single Chain Variable Fragments Antibodies
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Oh SH
- KMID: 1946167
- J Korean Pediatr Soc.
- 2002 Jun;45(6):691-699.
No abstract available. -
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- Anti-CD1a Single-Chain Fv Synthesis Using Phage Display and Flow Cytometry Screening
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Oh SH
- KMID: 2072510
- Korean J Pediatr Hematol Oncol.
- 2001 Oct;8(2):331-343.
PURPOSE: CD1a antigen is observed in diseases such as Langerhans cell histiocytosis, T cell acute lymphoblastic leukemia, acute myelogenous leukemia and CD1a presenting cells would be associated with transplantation... -
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- Production of Mouse Single Chain Fv Antibody to Surface Protein of Hepatitis B virus using Antibody Phage Display Library
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Choi IH, Kim HS, Kim IJ, Chung JH, Park SK
- KMID: 2001267
- J Korean Soc Microbiol.
- 1997 Aug;32(4):447-454.
In this study, we are to produce the single chain variable fragment (scFv) antibodies against surface protein of hepatitis B virus (HBV) using antibody phage display technique. Balb/c mice were... -
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- Resurrection of antibody as a therapeutic drug
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Chung HK, Chung JH
- KMID: 2150551
- Immune Netw.
- 2001 Apr;1(1):7-13.
- doi: 10.4110/in.2001.1.1.7
Currently 18 monoclonal antibodies were approved by FDA for inj ection into humans for therapeutic or diagnostic purpose. And 146 clinical trials are under way to evaluate the efficacy of... -
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- Serotype- and serogroup-specific detection of African horsesickness virus using phage displayed chicken scFvs for indirect double antibody sandwich ELISAs
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van Wyngaardt W, Mashau C, Wright I, Fehrsen J
- KMID: 1482819
- J Vet Sci.
- 2013 Mar;14(1):95-98.
- doi: 10.4142/jvs.2013.14.1.95
There is an ongoing need for standardized, easily renewable immunoreagents for detecting African horsesickness virus (AHSV). Two phage displayed single-chain variable fragment (scFv) antibodies, selected from a semi-synthetic chicken antibody... -
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- Application of bispecific antibody against antigen and hapten for immunodetection and immunopurification
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Kim H, Park S, Lee HK, Chung J
- KMID: 2154262
- Exp Mol Med.
- 2013 Sep;45(9):e43.
We present a bispecific antibody that recognizes an antigen and a hapten and can be applied to various biological assays, including immunoblotting and immunoprecipitation. In immunoblot analysis of serum, an... -
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- Isolation of Human scFv Antibodies Specific for House Dust Mite Antigens from an Asthma Patient by Using a Phage Display Library
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Jung WL, Lee HK, Yong TS, Cha SH
- KMID: 1571488
- Immune Netw.
- 2002 Jun;2(2):91-95.
- doi: 10.4110/in.2002.2.2.91
BACKGROUND: In order to characterize human antibodies with specificity for mite allergens at the molecular level, a scFv phage display library was constructed using peripheral blood mononuclear lymphocytes from an... -
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- Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library
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Yang W, Yoon A, Lee S, Kim S, Han J, Chung J
- KMID: 2375795
- Exp Mol Med.
- 2017 Mar;49(3):e308.
- doi: 10.1038/emm.2017.22
Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development... -
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- Development of Human Antibody Inhibiting RNase H Activity of Polymerase of Hepatitis B Virus Using Phage Display Technique
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Lee SR, Song EK, Jeong YJ, Lee YY, Kim IJ, Choi IH, Park SG
- KMID: 2054239
- Immune Netw.
- 2004 Mar;4(1):16-22.
- doi: 10.4110/in.2004.4.1.16
BACKGROUND: To develop a novel treatment strategy for hepatitis B virus infection, a major cause of liver chirosis and cancer, we aimed to make human monoclonal antibodies inhibiting RNase H... -
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- Isolation and Characterization of Human scFv Molecules Specific for Recombinant Human Heat Shock Protein (HSP) 70.1
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Baek HJ, Lee JS, Seo JS, Cha SH
- KMID: 2054238
- Immune Netw.
- 2004 Mar;4(1):7-15.
- doi: 10.4110/in.2004.4.1.7
BACKGROUND: The heat shock proteins (HSPs) play an important role in cellular protection mechanisms against physical or chemical stresses. In this study scFv antibodies specific for human HSP70.1 were isolated... -
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- Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
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Chang KH, Kim MS, Hong GW, Shin YN, Kim SH
- KMID: 1120142
- Exp Mol Med.
- 2012 Jan;44(1):52-59.
- doi: 10.3858/emm.2012.44.1.005
Epidermal growth factor receptor (EGFR) is an attractive target for tumor therapy because it is overexpressed in the majority of solid tumors and the increase in receptor expression levels has... -
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