- Single Cell RNA-Sequencing for the Study of Atherosclerosis
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Hajkarim M, Won KJ
- KMID: 2458380
- J Lipid Atheroscler.
- 2019 Sep;8(2):152-161.
- doi: 10.12997/jla.2019.8.2.152
Atherosclerosis is a major cause of coronary artery disease and stroke. A massive and new type of data has finally arrived in the field of atherosclerosis: single cell RNA sequencing... -
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- Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools
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Sierant MC, Choi J
- KMID: 2439207
- Genomics Inform.
- 2018 Dec;16(4):e17.
- doi: 10.5808/GI.2018.16.4.e17
Tumor heterogeneity, the cellular mosaic of multiple lineages arising from the process of clonal evolution, has continued to thwart multi-omics analyses using traditional bulk sequencing methods. The application of single-cell... -
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- Genetics of Alzheimer's Disease
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Kim JH
- KMID: 2442783
- Dement Neurocogn Disord.
- 2018 Dec;17(4):131-136.
- doi: 10.12779/dnd.2018.17.4.131
Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. Familial autosomal dominant AD genes founded by linkage analyses are APP, PSEN1, PSEN2, ABCA7, and SORL1. Genome-wide association... -
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- Optimized Methods of Preimplantation Genetic Diagnosis for Trinucleotide Repeat Diseases of Huntington's Disease, Spinocerebellar Ataxia 3 and Fragile X Syndrome
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Kim MJ, Lee HS, Lim CK, Cho JW, Kim JY, Koong MK, Song IO, Kang IS, Jun JH
- KMID: 1986938
- Korean J Reprod Med.
- 2007 Sep;34(3):179-188.
OBJECTIVES: Many neurological diseases are known to be caused by expansion of trinucleotide repeats (TNRs). It is hard to diagnose the alteration of TNRs with single cell level for preimplantation... -
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- Expressional Subpopulation of Cancers Determined by G64, a Co-regulated Module
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Min JW, Choi SS
- KMID: 2166528
- Genomics Inform.
- 2015 Dec;13(4):132-136.
- doi: 10.5808/GI.2015.13.4.132
Studies of cancer heterogeneity have received considerable attention recently, because the presence or absence of resistant sub-clones may determine whether or not certain therapeutic treatments are effective. Previously, we have... -
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