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Hepatocellular carcinoma surveillance in the 21st century: Saving lives or causing harm?

Hanouneh I, Alkhouri N, Singal AG

Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death worldwide. Prognosis and treatment options largely depend on tumor stage at diagnosis, with curative treatments only available...
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Non-alcoholic fatty liver disease-related hepatocellular carcinoma

Daher D, Dahan KSE, Singal AG

Non-alcoholic fatty liver disease (NAFLD), one of the most common causes of liver disease, is an increasingly common cause of hepatocellular carcinoma (HCC). Several demographic, clinical, and genetic factors contribute...
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Hepatocellular carcinoma surveillance in patients with non-alcoholic fatty liver disease

Seif El Dahan K, Daher D, Singal AG

Non-alcoholic fatty liver disease (NAFLD) may progress to cirrhotic or non-cirrhotic hepatocellular carcinoma (HCC), and is currently recognized as the fastest growing cause of HCC worldwide. Accordingly, professional society guidelines...
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Body Composition Predicts Survival in Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolization

Parikh ND, Zhang P, Singal AG, Derstine B, Krishnamurthy V, Barman P, Waljee AK, Su GL

PURPOSE: The prognosis of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE) is often uncertain. We aimed to utilize analytic morphomics, a high-throughput imaging analysis, to assess if body...
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Factors associated with unrecognized cirrhosis in patients with hepatocellular carcinoma

Lee YT, Karim MA, Kum HC, Park S, Rich NE, Noureddin M, Singal AG, Yang JD

Background/Aims: Cirrhosis is the most important risk factor of hepatocellular carcinoma (HCC), and patients with cirrhosis are recommended to receive semiannual surveillance for early HCC detection. However, early cirrhosis is...
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