- Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Elastin Scaffold Remodeling in Diabetes
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Chow JP, Simionescu DT, Carter AL, Simionescu A
- KMID: 2360882
- Tissue Eng Regen Med.
- 2016 Dec;13(6):701-712.
- doi: 10.1007/10.1007/s13770-016-0018-x
Diabetes is a major risk factor for the progression of vascular disease, contributing to elevated levels of glycoxidation, chronic inflammation and calcification. Tissue engineering emerges as a potential solution for... -
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- Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells
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Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D
- KMID: 2360799
- Tissue Eng Regen Med.
- 2016 Oct;13(5):507-515.
- doi: 10.1007/s13770-016-9114-1
The goal of this study was to test the hypothesis that stem cells, as a response to valve-specific extracellular matrix “niches†and mechanical stimuli, would differentiate into valvular interstitial cells... -
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