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Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis

Ha KB, Lee ES, Park NW, Jo SH, Shim S, Kim DK, Ahn CM, Chung CH

Background: Curcumin 2005-8 (Cur5-8), a derivative of curcumin, improves fatty liver disease via AMP-activated protein kinase activation and autophagy regulation. EW-7197 (vactosertib) is a small molecule inhibitor of transforming growth...
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Effects of cancer stigma on quality of life of patients with hepatobiliary and pancreatic cancer

Kim N, Kang D, Shin SH, Heo JS, Shim S, Lim J, Cho J, Han IW

Backgrounds/Aims: Cancer stigma (CS), a self-inflicted sense of hopelessness, has been identified as a major factor affecting cancer patients’ outcomes. However, few studies have investigated the CS-related outcomes in hepatobiliary...
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Psychometric Validation of the Korean Version of the Cancer Survivors’ Unmet Needs (CaSUN) Scale among Korean Non–Small Cell Lung Cancer Survivors

Kang D, Lee G, Kim S, Nam H, Kong S, Shim S, Lee JK, Jung W, Shin S, Kim HK, Zo JI, Shim YM, Shin DW, Cho J

Purpose The purpose of the study was to validate the Korean version of Cancer Survivors’ Unmet Needs (CaSUN) scale among non–small cell lung cancer survivors. Materials and Methods Participants were recruited...
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Ideal cardiovascular health metrics and the risk of nonalcoholic fatty liver disease in Korean adults

Shim S, Jung S, Kim S, Kim H

Background: The association between cardiovascular risk factors and nonalcoholic fatty liver disease (NAFLD) is well established, but whether cardiovascular health (CVH) metrics is associated with NAFLD had not been fully...
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A Patient with Tuberous Sclerosis with Hemimegalencephaly Presenting with In tractable Epilepsy in the Early Neonatal Period: A Case Report

Shim S, Shin JE, Lee SM, Baek SH, Park JS, Han JH, Park MS, Kang HC, Park EK, Eun HS

Hemimegalencephaly (HME) is a rare disease characterized by partial or complete hypertrophy of one cerebral hemisphere. It is associated with intractable seizures, developmental delay, hemiparesis, and other neurological symptoms. Tuberous...
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Comparisons of Fit Factors Between Two Quantitative Fit Testers (PortaCount vs. MT)

Han DH, Seo H, Kang Bk, Jang H, Kim H, Shim S

This study evaluated the consistency between two quantitative fit test devices with different methods of ambient aerosol counting. Three types of respirators (N95, half mask, and full facepiece) were worn...
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Development and validation of interpretable machine learning models for inpatient fall events and electronic medical record integration

Shim S, Yu JY, Jekal S, Song YJ, Moon KT, Lee JH, Yeom KM, Park SH, Cho IS, Song MR, Heo S, Hong JH

Objective Falls are one of the most frequently occurring adverse events among hospitalized patients. The Morse Fall Scale, which has been widely used for fall risk assessment, has the two...
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Fear of Cancer Recurrence and Its Negative Impact on Health-Related Quality of Life in Long-term Breast Cancer Survivors

Tran TXM, Jung SY, Lee EG, Cho H, Kim NY, Shim S, Kim HY, Kang D, Cho J, Lee E, Chang YJ, Cho H

Purpose Fear of cancer recurrence (FCR) is a common psychological issue in breast cancer (BC) survivors during early survivorship but whether the same is true among long-term survivors has yet...
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NADPH oxidase inhibitor development for diabetic nephropathy through water tank model

Lee HE, Shim S, Choi Y, Bae YS

Oxidative stress can cause generation of uncontrolled reactive oxygen species (ROS) and lead to cytotoxic damage to cells and tissues. Recently, it has been shown that transient ROS generation can...
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Validation of Korean Version of the COmprehensive Score for financial Toxicity (COST) Among Breast Cancer Survivors

Shim S, Kang D, Kim N, Han G, Lim J, Kim H, Park J, Lee M, Lee JE, Kim SW, Yu J, Chae BJ, Ryu JM, Nam SJ, Lee SK, Cho J

Purpose Little is known about the impact of financial toxicity in disease-free breast cancer survivors. We aim to validate the COmprehensive Score for financial Toxicity in Korean (COST-K) and evaluate...
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Cumulative Recurrence Rate and Risk Factors for Recurrent Abdominal Wall Endometriosis after Surgical Treatment in a Single Institution

Kim SJ, Choi SH, Won S, Shim S, Lee N, Kim M, Kim MK, Seong SJ, Kim ML

Purpose: This study aimed to evaluate the cumulative recurrence rate and risk factors for recurrent abdominal wall endometriosis (AWE) after surgical treatment. Materials and Methods: A retrospective cohort study was conducted...
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EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation

Ha KB, Sangartit W, Jeong AR, Lee ES, Kim HM, Shim S, Kukongviriyapan U, Kim DK, Lee EY, Chung CH

Background: Diabetic nephropathy (DN) is characterized by albuminuria and accumulation of extracellular matrix (ECM) in kidney. Transforming growth factor-β (TGF-β) plays a central role in promoting ECM accumulation. We aimed...
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Validation of the Korean Version of the Patient-Reported Outcomes Measurement Information System 29 Profile V2.1 among Cancer Survivors

Kang D, Kim Y, Lim J, Yoon J, Kim S, Kang E, Nam H, Shim S, Lee M, Bok H, Lee SW, Shin SY, Ahn JS, Oh D, Cho J

Purpose The purpose of the study was to validate the Korean version of Patient-Reported Outcomes Measurement Information System 29 Profile v2.1 (K-PROMIS-29 V2.1) among cancer survivors. Materials and Methods Participants were...
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Updates on Therapeutic Alternatives for Genitourinary Syndrome of Menopause: Hormonal and Non-Hormonal Managements

Shim S, Park KM, Chung YJ, Kim MR

Postmenopausal atrophic vaginitis, along with vasomotor symptoms and sleep disorders, is one of the most troublesome symptoms of menopause. However, many women do not manage this symptom properly due to...
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Differences in Cognitive and Psychological Characteristics of Psychiatric Patients with Military Service Issues versus General Psychiatric Outpatients

Shim S, Choi J, Kim E

Objectives:The purpose of this study was to examine cognitive and psychological characteristics of patients with military service suitability issues compared to the general psychiatric outpatients. Methods:108 patients who visited psychiatric clinic...
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The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene

Kim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim S

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a positive-sense singlestranded RNA (+ssRNA) that causes coronavirus disease 2019 (COVID-19). The viral genome encodes twelve genes for viral replication and infection....
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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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Systematic Review of Studies Assessing the Health-Related Quality of Life of Hepatocellular Carcinoma Patients from 2009 to 2018

Kang D, Shim S, Cho J, Lim HK

We reviewed all studies assessing the health-related quality of life (HRQoL) in patients with hepatocellular carcinoma (HCC) between 2009 and 2018 (n = 45). Most studies assessed HRQoL as an...
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Early and Delayed Postoperative Rehabilitation after Arthroscopic Rotator Cuff Repair: A Comparative Study of Clinical Outcomes

Choi S, Seo KB, Shim S, Shin JY, Kang H

BACKGROUND: The duration of immobilization after arthroscopic rotator cuff repair and the optimal time to commence rehabilitation are still the subject of ongoing debates. This study was undertaken to evaluate...
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Evaluation of the immunobiological effects of a regenerative far-infrared heating system in pigs

Kim S, Park HT, Soh SH, Oh MW, Shim S, Yoo HS

Thermal conditions are an important environmental factor in maintaining healthy pigs because they affect feed intake, growth efficiency, reproduction and immune responses in pigs. RAVI, a regenerative far-infrared heating system,...
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