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Factors for Endoscopic Submucosal Dissection in Early Colorectal Neoplasms: A Single Center Clinical Experience in China

He YQ, Wang X, Li AQ, Yang L, Zhang J, Kang Q, Tang S, Jin P, Sheng JQ

BACKGROUND/AIMS: Early colorectal (CR) neoplasm can be cured by endoscopic submucosal dissection (ESD), but clinical experience and factors associated with complications from ESD for CR neoplasms in China have not...
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Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells

He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J

  • KMID: 1402316
  • Exp Mol Med.
  • 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors....
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Adalimumab induction and maintenance therapy achieve clinical remission and response in Chinese patients with Crohn's disease

Wu KC, Ran ZH, Gao X, Chen M, Zhong J, Sheng JQ, Kamm MA, Travis S, Wallace K, Mostafa NM, Shapiro M, Li Y, Thakkar RB, Robinson A

BACKGROUND/AIMS: This was a Phase 2 study (NCT02015793) to evaluate the pharmacokinetics, safety, and efficacy of adalimumab in Chinese patients with Crohn's disease (CD). METHODS: Thirty, adult Chinese patients with CD...
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