- Alleviation of γ-enolase decrease by the chlorogenic acid administration in the stroke animal model
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Kang JB, Shah MA, Ko MS, Koh PO
- KMID: 2543752
- Korean J Vet Res.
- 2023 Mar;63(1):e6.
- doi: 10.14405/kjvr.20230008
Stroke is a major cause of death and long-term disability. Chlorogenic acid is a phenolic compound with a potent neuroprotective effect. γ-enolase is a phosphopyruvate hydratase found in mature neurons... -
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- Quercetin ameliorates glutamate toxicity-induced neuronal cell death by controlling calcium-binding protein parvalbumin
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Kang JB, Kang JB, Park DJ, Shah MA, Koh PO
- KMID: 2527878
- J Vet Sci.
- 2022 Mar;23(2):e26.
- doi: 10.4142/jvs.21273
Background: Glutamate is the main excitatory neurotransmitter. Excessive glutamate causes excitatory toxicity and increases intracellular calcium, leading to neuronal death. Parvalbumin is a calcium-binding protein that regulates calcium homeostasis. Quercetin... -
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- Chlorogenic acid alleviates the reduction of Akt and Bad phosphorylation and of phospho-Bad and 14-3-3 binding in an animal model of stroke
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Shah MA, Kang JB, Kim MO, Koh PO
- KMID: 2536696
- J Vet Sci.
- 2022 Nov;23(6):e84.
- doi: 10.4142/jvs.22200
Background: Stroke is caused by disruption of blood supply and results in permanent disabilities as well as death. Chlorogenic acid is a phenolic compound found in various fruits and coffee... -
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- Baicalin alleviates lipopolysaccharide-induced neuroglial activation and inflammatory factors activation in hippocampus of adult mice
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Shah MA, Park DJ, Kang JB, Koh PO, Kim MO
- KMID: 2507240
- Lab Anim Res.
- 2020 Sep;36(3):268-278.
- doi: 10.1186/s42826-020-00058-w
Baicalin is a natural flavonoid that exerts a variety of pharmaceutical effects such as anti-inflammatory and antioxidant. Lipopolysaccharide (LPS) is an endotoxin that releases inflammatory cytokines and induces inflammatory response.... -
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- Retinoic acid regulates the ubiquitin– proteasome system in a middle cerebral artery occlusion animal model
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Kang JB, Shah MA, Park DJ, Koh PO
- KMID: 2530959
- Lab Anim Res.
- 2022 Jun;38(2):99-109.
- doi: 10.1186/s42826-022-00123-6
Background: Retinoic acid is a major metabolite of vitamin A and exerts beneficial effects including anti-oxidant and anti-inflammatory activities in neurons. The ubiquitin–proteasome system is an important biological system that... -
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- Molecular detection and characterization of ovine herpesvirus-2 using heminested PCR in Pakistan
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Riaz A, Dry I, Dalziel R, Rehman SU, Shah MA, Akhtar HMN, Yousaf A, Baig R
- KMID: 2518807
- J Vet Sci.
- 2021 Jul;22(4):e51.
- doi: 10.4142/jvs.2021.22.e51
Background: Malignant catarrhal fever (MCF) is a highly fatal lymphoproliferative disease of cattle, deer, bison, water buffalo, and pigs caused by the gamma-herpesviruses alcelaphine herpesvirus-1 (AlHV-1) and ovine herpesvirus-2 (OvHV-2). Objectives:... -
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- Lipopolysaccharide induces neuroglia activation and NF-κB activation in cerebral cortex of adult mice
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Kang JB, Park DJ, Shah MA, Kim MO, Koh PO
- KMID: 2470009
- Lab Anim Res.
- 2019 Oct;35(3):132-139.
- doi: 10.1186/s42826-019-0018-9
Lipopolysaccharide (LPS) acts as an endotoxin, releases inflammatory cytokines, and promotes an inflammatory response in various tissues. This study investigated whether LPS modulates neuroglia activation and nuclear factor kappa B... -
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- Hyperglycemia aggravates decrease in alpha-synuclein expression in a middle cerebral artery occlusion model
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Kang JB, Kim DK, Park DJ, Shah MA, Kim MO, Jung EJ, Lee HS, Koh PO
- KMID: 2459295
- Lab Anim Res.
- 2018 Dec;34(4):195-202.
- doi: 10.5625/lar.2018.34.4.195
Hyperglycemia is one of the major risk factors for stroke. Hyperglycemia can lead to a more extensive infarct volume, aggravate neuronal damage after cerebral ischemia. α-Synuclein is especially abundant in... -
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