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Serotonin Syndrome After an Overdose of Dextromethorphan and Chlorpeniramine: Two Case Reports

Jung KY, Yun SH, Jung HM, Kim JH, Han SB, Kim JS, Paik JH

  • KMID: 1482713
  • J Korean Soc Clin Toxicol.
  • 2013 Jun;11(1):19-22.
Dextromethorphan and chlorpeniramine are common ingredients of over-the-counter (OTC) cough pills. They are known to be safe when used alone, however, combination with other serotonergic drugs or use of an...
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A Case of Serotonin Syndrome Induced by Fluoxetine and Duloxetine Independently in a Same Patient

You S, Noh JS

  • KMID: 2287474
  • Korean J Psychopharmacol.
  • 2012 Apr;23(2):74-77.
Here we report a case of serotonin syndrome caused by fluoxetine 20 mg and duloxetine 60 mg independently eight week apart. A 65-year old man developed fever, agitation and change...
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Two Cases of Serotonin Syndrome

Kwak YT, Han IW, Kang SS, Koo MS, Kim OJ

  • KMID: 1905142
  • J Korean Neurol Assoc.
  • 1999 Jul;17(4):591-596.
We report 2 cases of serotonin syndrome with variable symptoms after being treated with antidepressants. A 57-year-old woman developed agitation, diaphoresis, and tremor after combination therapy with fluoxetine and trazodone....
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Outlook of Future Serotonergic Drugs and Their Clinical Usefulness: Focused on Schizophrenia and Depression

Kim YK

  • KMID: 2287362
  • Korean J Psychopharmacol.
  • 2006 May;17(3):273-282.
Serotonin has been implicated in the etiology and pathophysiology of mental illness such as depression, schizophrenia, anxiety disorder, eating disorder, obsessive compulsive disorder, and panic disorder. Many current used treatments...
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Evidence for Peripheral Effect of Serotonin on Ejaculatory Response

Paick JS, Park DW, Son H, Lee SH, Kim SW

  • KMID: 1859356
  • Korean J Androl.
  • 2001 Dec;19(3):163-171.
PURPOSE: Although serotonin (5-HT) has been implicated in central control of sexual desire, erection and ejaculation, its peripheral effect has been poorly studied. Here, we investigated the peripheral effects of...
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The Role of 5-HT Receptors on the Acetylcholine Release from the Rat Striatum

Joo YH, Jung KY, Choi BK

  • KMID: 1607282
  • Korean J Psychopharmacol.
  • 2001 Jun;12(2):140-146.
The aim of this study was to investigate the role of the 5-HT receptors in acetylcholine (ACh) release from the striatum. Slices from the rat striatum and synaptosomes were incubated...
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Investigation of the Validity of an in vivo Experimental Model for the Evaluation of the Therapeutic Potentials of Drugs for the Treatment of Premature Ejaculation

Baek MK, Kim SW, Paick JS

  • KMID: 2292261
  • Korean J Urol.
  • 2002 Nov;43(11):969-975.
PURPOSE: The purpose of this study was to investigate the validity of in vivo experimental models to evaluate the therapeutic potentials of drugs for the treatment of premature ejaculation. MATERIALS AND...
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Serotonin Syndrome after Clomipramine Overdose in a Child

Direk MC, Yıldırım V, Güneş S, Bozlu G, Okuyaz C

Serotonin syndrome (SS) is a potentially life-threatening condition associated with increased serotonergic activity in central nervous system and may occur during the use of serotonergic drugs. Although increasing frequency of...
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Antidepressant-Like Effects of Lycii Radicis Cortex and Betaine in the Forced Swimming Test in Rats

Kim SJ, Lee MS, Kim JH, Lee TH, Shim I

  • KMID: 2170690
  • Biomol Ther.
  • 2013 Jan;21(1):79-83.
The purpose of the present study was to examine the effect of Lycii Radicis Cortex (LRC) and betaine (BT) on immobility and neurochemical change in the forced swimming test (FST)...
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Preventive Effect of Serotonergic Drugs on LPS-Induced Acute Anorexia in Rats

Park SY, Kim KH, Ahn DK, Park TI, Kim JY, Kim YW, Lee DC, Lee SK

  • KMID: 1600056
  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):149-153.
The aim of the present study was to determine whether serotonergic drugs could reverse lipopolysaccharide (LPS) -induced anorexia in rats. LPS (500microgram/kg body weight) and all serotonergic drugs, except for...
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Gastroparesis and Functional Dyspepsia: A Blurring Distinction of Pathophysiology and Treatment

Kim BJ, Kuo B

  • KMID: 2433495
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):27-35.
  • doi: 10.5056/jnm18162
Gastroparesis and functional dyspepsia are 2 of the most common gastric neuromuscular disorders. These disorders are usually confused, having both similarities and differences. The pathophysiology of these disorders involves abnormal...
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A Case of Postpartum Reversible Cerebral Vasoconstriction Syndrome

Lee HJ, Lee DH, Jung HC, Moon KW

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by development of a severe thunderclap headache with or without other acute neurological symptoms, and by multifocal or diffuse segmental vasoconstriction of the...
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Chronotype in Relation to Bipolarity, Suicidal Ideation, and Auditory Evoked Potentials in Patients with Major Depressive Disorder : Preliminary Study

Park YM, Lee SH

  • KMID: 2029088
  • Korean J Biol Psychiatry.
  • 2014 Feb;21(1):14-20.
OBJECTIVES: The current study investigated the putative relationship between chronotype and suicidality or bipolarity in patients with major depressive disorder (MDD). METHOD: Nineteen outpatients who met the criteria for MDD according...
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FOS-like Immunoreactivity in Rat Brain Induced by Haloperidol, Clozapine, and Haloperidol Combined with Serotonergic Agents

Kim KS, Bahk WM, Sei SW

  • KMID: 2286970
  • Korean J Psychopharmacol.
  • 1998 Apr;9(1):49-57.
OBJECTIVES: The purpose of this study was to investigate the differences between potential neuroanatomical sites of action of(1) a typical antipsychotic drug (haloperidol), (2) an atypical antipsychotic drug (clozapine), and...
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Effects of Serotonergic Drugs on Intraluminal Pressure of Vas Deferens Induced by Electrical Stimulation of Rat Hypogastric Nerve

Seo KK, Kwak SM, Kim SC

  • KMID: 2298637
  • Korean J Androl.
  • 1999 Aug;17(2):99-106.
PURPOSE: To compare the effects of various serotonergic drugs on the inhibition of intraluminal pressure rise in the rat vas deferens induced by electrical stimulation of the hypogastric nerve. MATERIAL AND...
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