- Association between Schizophrenia and the T102C Polymorphism of the 5-HT2A
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Lee MS, Nam JW, Kwak DI
- KMID: 2334570
- J Korean Soc Biol Psychiatry.
- 1998 Nov;5(2):215-218.
The 5-HT2A receptor is of great interest for research into schizophrenia and psychopharmacology in light of the observation that schizophrenic patients has 5-HT cortical-subcortical imbalance and atypical antipsychotic clozpine has... -
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- Effect of Centrally-administered DOI, a 5-HT2 Receptor Agonist, on the Regulation of Rabbit Renal Nerve Activities
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Lim YC, Kim HJ, Baik YH
- KMID: 2116754
- Chonnam Med J.
- 2002 Jun;38(2):99-106.
Centrally-administered DOI [1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane HCl], a selective 5-HT2 agonist, has been observed to elicit antidiuresis and antinatriuresis in rabbits. Renal nerves has been suggested to be closely related with this renal... -
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- Effect of 5-HT2c Receptor Modulation on the m-Chlorophenlpiperazine-Induced Hypoactivity
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Jang WS, Byun WT, Chung YI, Lee WS
- KMID: 2287000
- Korean J Psychopharmacol.
- 1997 Apr;8(1):107-112.
It was aimed to investigate the effect of 5-HT2C receptor modulation on the rat behavioral responses induced by 1-(m-chlorophenyl) piperazine(mCPP), a major metabolite of trazodone. The animal activities(ambulation, stereotypy and... -
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- Serotonin(5-HT): can it be a cause in overactive bladder
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Kim HJ, Lee SJ
- KMID: 2330455
- J Korean Continence Soc.
- 2001 Jun;5(1):39-47.
- doi: 10.5213/jkcs.2001.5.1.39
PURPOSE: The purpose of this study is to investigate in vitro the effects of serotonin on the rat detrusor. In particular, this study examines what drugs inhibit the serotonin-induced detrusor... -
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- Nefazodone and Associated Perceptual Disturbance : A Report of Four Cases
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Kim JY, Song HS, Cho BH, Kim YK
- KMID: 2334628
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):259-263.
Nefazodone, a newer antidepressant is a phenylpiperazine derivative that inhibits the reuptake of both norepinephrine and serotonin, and antagonizes 5-HT2A and alpha1 adrenergic receptors. Compared with SSRIs nefazodone caused the... -
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- Role of 5-HT2A Receptor Gene T102C Polymorphism in Coronary Artery Disease and Serum Lipid Level
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Choi JH, Zhang SY, Cho YS, Whang KK, Lee JH, Oh S, Chae IH, Zo JH, Kim HS, Oh BH, Lee MM, Choi YS, Park YB
- KMID: 2093863
- Korean Circ J.
- 2003 Apr;33(4):269-276.
- doi: 10.4070/kcj.2003.33.4.269
BACKGROUND AND OBJECTIVES: The 5-HT2A receptor is one of the main mediators of a serotonin-evoked coronary artery contraction. This is because vasoconstriction is selectively blocked by the 5-HT2 receptor antagonist,... -
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- Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase
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Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM
- KMID: 2154286
- Exp Mol Med.
- 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We... -
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