- APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia
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Kim H, Seo H, Park Y, Min BJ, Seo ME, Park KD, Shin HY, Kim JH, Kang HJ
- KMID: 2417871
- Cancer Res Treat.
- 2018 Jul;50(3):823-834.
- doi: 10.4143/crt.2017.351
PURPOSE: Mercaptopurine (MP) is one of the main chemotherapeutics for acute lymphoblastic leukemia (ALL). To improve treatment outcomes, constant MP dose titration is essential to maintain steady drug exposure, while... -
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- Flat Pattern Peaks of Tacrolimus Absorption and Associated Pharmacogenomic Variants in Kidney Transplantation Recipients
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Kim SM, Lim Y, Min S, Min BJ, Seo ME, Lee KH, Kim JH, Ha J
- KMID: 2525485
- J Korean Med Sci.
- 2022 Feb;37(5):e33.
- doi: 10.3346/jkms.2022.37.e33
Background: Tacrolimus is the most commonly used immunosuppressive drug in solid organ transplantation. After administering a conventional twice-daily dose of tacrolimus, peak levels were achieved within the first 1.5 to... -
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