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Sendai F/HN Viroplexes for Efficient Transfection of Leukemic T Cells

Kim JS, Lee YK, Jeong HY, Kang SJ, Kim MW, Ryu SH, Kim HS, Kim KS, Kim DE, Park YS

PURPOSE: Most chemical transfection reagents are ineffective for the transfection of cells in suspension, such as leukemic cell and stem cell lineages. We developed two different types of viroplexes, cationic...
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Microbiological Contamination of Laboratory Mice and Rats in Korea from 2007 to 2008

Won YS, Kwon HJ, Kim SW, Han JT, Lee SB, Nam KH, Yoon WK, Kim KH, Moon OS, Kim HC

In order to assess the microbiological contamination of laboratory mice and rats in Korea over the 2-year period from 2007 to 2008, we monitored animals housed in mouse and rat...
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Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients

Lee M, Sim H, Ahn H, Ha J, Baek A, Jeon YJ, Son MY, Kim J

In Parkinson’s disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as in vitro models. The advancement in the field of reprogramming technology has provided...
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Insulin Gene Therapy Using HVJ-liposome and Epstein-Barr Virus Plasmid in Murine Streptozotocin Induced Diabetes

Kim YD, Park KG, Han SW, Ahn JD, Lee HJ, Kim MJ, Kim HS, Park NH, Lee IK

  • KMID: 1515209
  • J Korean Diabetes Assoc.
  • 2003 Oct;27(5):405-413.
BACKGROUND: Despite improvement in insulin preparation and delivery, the use of insulin therapy alone to maintain normal glucose concentration and prevent the development of diabetic complication is not easy. Therefore,...
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The Effect of Ribbon-Type Antisense Oligodeoxynucleotides for Transforming Growth Factor-beta1 in Unilateral Ureteral Obstruction

Han SM, Kim EJ, Jeoung HS, Lee BY, Lee SS, Park KK, Kim HC

  • KMID: 2073725
  • Korean J Pathol.
  • 2002 Apr;36(2):84-92.
BACKGROUND: In unilateral ureteral obstruction (UUO), the obstructed kidney is characterized by interstitial fibrosis and an increase in transforming growth factor (TGF)-beta1. Interstitial expression of TGF-beta1 is important in tublointerstitial...
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The Effect of Antibody and Gene Therapy for Transforming Growth Factor- 1 on Scar Formation

Kim JH, Han KH, Ahn JD, Lee IK, Kim EJ, Hwang MY, Park KK

  • KMID: 1725836
  • Korean J Pathol.
  • 2001 Oct;35(5):424-432.
BACKGROUND: Transforming growth factor (TGF)- has a large variety of biological functions, including the modulation of inflammation and the immune system, and is presumed to play important roles in repairing...
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The Effects of Nuclear Factor-kappa B Decoy Oligodeoxynucleotide on Lipopolysaccharide-Induced Direct Acute Lung Injury

Kim JH, Yoon DW, Jung KH, Kim HO, Ha ES, Lee KJ, Hur GY, Lee SY, Lee SY, Shin C, Shim JJ, In KH, Yoo SH, Kang KH

  • KMID: 2319210
  • Tuberc Respir Dis.
  • 2009 Aug;67(2):95-104.
BACKGROUND: The pathophysiologic mechanisms of early acute lung injury (ALI) differ according to the type of primary insult. It is important to differentiate between direct and indirect pathophysiologic pathways, and...
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