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Glycobiology of Selectin

Kim YS, Ko JH

Selectins, carbohydrate-binding molecules, bind to fucosylated and sialylated glycoprotein ligands, and are found on endothelial cells, leukocytes and platelets. They can be classified into E-, L- and P-selectins, and are...
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Selectins: functional importance as cell adhesion molecule in immune system

Noh Y, Cho D, Ko H, Lim D, Chai HH

Selectins are cell membrane glycoproteins that recognize specific glycoconjugates expressed on the surface of cells. Then, selectins adjust cell-cell interactions that are important in inflammation, hemostasis and cancer metastasis. Selectins...
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Antagonism of licorice on selectin-mediated eodinophil and neutrophil adhesion

Kim MK

  • KMID: 2286174
  • J Asthma Allergy Clin Immunol.
  • 1998 Mar;18(1):61-68.
BACKGROUND AND OBJECTIVE: Early in inflammation, adhesion occurs between leukocytes and endothelium where selectins bind to sialyl Lewis x(Sle,) and related oligosaccharides. We tested glycerrhetinic acid(GA), msjor anti-inflammmatory component of licorice, for its...
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Expression of Adhesion Molecules in IgA Nephropathy, Diffuse Crescentic Glomerulonephritis, and Minimal Change Disease

Moon KC, Park SY, Kim HW, Lee HS

  • KMID: 2275654
  • Korean J Pathol.
  • 2000 May;34(5):331-340.
Accumulation of leukocytes within the glomerulus is a key event in the pathogenesis of glomerulonephritis. This process is mediated by pairs of adhesion molecules. We have examined the expression pattern...
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E-selectin Mrna and Protein Expression Increase Transiently After Unilateral Cerebral hypoxia-ischemia in Neonatal Rats

Eun BL

  • KMID: 2177120
  • J Korean Child Neurol Soc.
  • 1998 May;5(2):228-234.
BACKGROUND AND PURPOSE: The selectins play a role in the initiation of endothelium-leukocyte interaction; endothelial expression of E-selectin is induced by ischemia-reperfusion-like conditions in vitro. Neutrophils accumulate in post-hypoxic-ischemic neonatal...
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Expression of the ED3 Antigen and its Upregulation after Cyclophosphamide Treatment on Basal Epithelial Cells of Rat Stratified Squamous Epithelium

Choi HU, Lee SK, Shim NR, Lee HW, Baek SY, Kim JB, Kim BS, Yoon S

  • KMID: 1894512
  • Korean J Anat.
  • 2003 Feb;36(1):1-10.
Sialoadhesin (Sn) expression has been demonstrated on murine and rat macrophages in lymphatic organs and is recognized by the monoclonal antibody (mAb) ED3 in the rat. Sialoadhesin (Siglec-1), the ED3...
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The effect of mesenchymal stem cell use on intra-abdominal adhesions in a rat model

Karaca G, Pehlivanli F, Aydin O, Altunkaya , Uzun H, Niyaz M, Özden H, Bulut H

PURPOSE: Intra-abdominal adhesions (IAA) are among the most frequently seen pathologies in general surgery practice with an increased morbidity and mortality. In the present study, we investigated the effect of...
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