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Selectins, carbohydrate-binding molecules, bind to fucosylated and sialylated glycoprotein ligands, and are found on endothelial cells, leukocytes and platelets. They can be classified into E-, L- and P-selectins, and are...
Selectins are cell membrane glycoproteins that recognize specific glycoconjugates expressed on the surface of cells. Then, selectins adjust cell-cell interactions that are important in inflammation, hemostasis and cancer metastasis. Selectins...
BACKGROUND AND OBJECTIVE: Early in inflammation, adhesion occurs between leukocytes and
endothelium where selectins bind to sialyl Lewis x(Sle,) and related oligosaccharides.
We tested glycerrhetinic acid(GA), msjor anti-inflammmatory component of licorice, for
its...
Accumulation of leukocytes within the glomerulus is a key event in the pathogenesis of
glomerulonephritis. This process is mediated by pairs of adhesion molecules. We have examined
the expression pattern...
BACKGROUND AND PURPOSE: The selectins play a role in the initiation of endothelium-leukocyte interaction; endothelial expression of E-selectin is induced by ischemia-reperfusion-like conditions in vitro. Neutrophils accumulate in post-hypoxic-ischemic neonatal...
Choi HU, Lee SK, Shim NR, Lee HW, Baek SY, Kim JB, Kim BS, Yoon S
KMID: 1894512
Korean J Anat.
2003 Feb;36(1):1-10.
Sialoadhesin (Sn) expression has been demonstrated on murine and rat macrophages in lymphatic organs and is recognized by the monoclonal antibody (mAb) ED3 in the rat. Sialoadhesin (Siglec-1), the ED3...
PURPOSE: Intra-abdominal adhesions (IAA) are among the most frequently seen pathologies in general surgery practice with an increased morbidity and mortality. In the present study, we investigated the effect of...