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Effects of Lipoxygenase Inhibitor on Diabetic Nephropathy in Rats: Decreasing Proteinuria and Preserving Renal Function

Chung HC, Kim IY, Kim SR, Son J, Lee DW, Song SH, Seong EY, Kwak IS, Lee SB

  • KMID: 2252632
  • Korean J Nephrol.
  • 2011 Sep;30(5):452-458.
PURPOSE: Oxidative stress leads to an increased production of lipoxygenase derivatives in diabetic nephropathy. Thus, we hypothesized that lipoxygenase inhibitor, nordihydroguaiaretic acid (NDGA), ha the effects of decreasing proteinuria and...
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Cryopreservation of Collected Peripheral Blood Hematopoietic Stem Cell Product with 5% DMSO by Adding Nontoxic Natural Cryoprotectants

Hamm JY, Shon YH, Suh JS

  • KMID: 1442287
  • Korean J Blood Transfus.
  • 2011 Aug;22(2):89-98.
BACKGROUND: Cryopreservation of hematopoietic stem cells has become an important process due to the therapeutic protocol, which includes stem cell transplantation after chemotherapy, for many hematological malignancies. The conventional medium...
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Enhanced Cardiomyogenic Differentiation of P19 Embryonal Carcinoma Stem Cells

Yang J, Ko SJ, Kim BS, Kim HS, Park S, Hong D, Hong SW, Choi JH, Park CY, Choi SC, Hong SJ, Lim DS

BACKGROUND AND OBJECTIVES: We investigated the effects of different concentrations of serum, 5-azacytidine, and culture time on the cardiomyogenic differentiation of P19 embryonal carcinoma stem cells in the course of...
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alpha-Tocopheryl Succinate Inhibits Osteoclast Formation by Suppressing Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL) Expression and Bone Resorption

Kim HN, Lee JH, Jin WJ, Lee ZH

OBJECTIVE: Osteoclasts are bone-resorbing multinucleated cells derived from the monocyte/macrophage lineage during normal and pathological bone turnover. Recently, several studies revealed that alpha-tocopheryl succinate (alphaTP-suc) have demonstrated potent anti-cancer activities...
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