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Comparison between Therapeutic Efficacies of Histone Deacetylase Inhibitors and Established Drug Regimens Against Breast Cancer Cells using the Histoculture Drug Response Assay

Seo JY, Lee YM, Cho DH, Roh SA, Ro SG, Hyun YL, Kim SY, Kim YS, Kim TW, Ahn SH, Kim JC

PURPOSE: Histone deacetylase inhibitors (HDACIs) induce accumulation of acetylated histones in nucleosomes, which lead to reactivate gene expression and inhibit the growth and survival of tumor cells. This study evaluated...
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