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Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content

Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ

The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which...
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Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic beta cells

Ma WN, Park SY, Han JS

As glucose is known to induce insulin secretion in pancreatic beta cells, this study investigated the role of a phospholipase D (PLD)-related signaling pathway in insulin secretion caused by high...
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