- Ethanol Extract of Cirsium japonicum var. ussuriense Kitamura Exhibits the Activation of Nuclear Factor Erythroid 2-Related Factor 2-dependent Antioxidant Response Element and Protects Human Keratinocyte HaCaT Cells Against Oxidative DNA Damage
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Yoo OK, Choi BY, Park JO, Lee JW, Park BK, Joo CG, Heo HJ, Keum YS
- KMID: 2161526
- J Cancer Prev.
- 2016 Mar;21(1):66-72.
- doi: 10.15430/JCP.2016.21.1.66
Keratinocytes are constantly exposed to extracellular insults, such as ultraviolet B, toxic chemicals and mechanical stress, all of which can facilitate the aging of keratinocytes via the generation of intracellular... -
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- Immunohistochemical Expression of Nuclear Retinoid Receptor and CREB(cAMP Response Element Binding Protein) in Lung Cancers
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Shin JW, Paik KH, Choi W, Park IW, Kim MK
- KMID: 2318749
- Tuberc Respir Dis.
- 2005 Dec;59(6):631-637.
BACKGROUND: Transcriptional factors of the CREB(cAMP Response Element Binding Protein) are involved in the regulation of gene expression in response to a variety of signaling pathways. Proteins produced by the... -
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- The Effect of T3 on Thyroid Hormone Receptor Dynamics in Thyroid Hormone Response Element of Chicken Lysozyme Silencer
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Lee SJ, Park CY, Jeong IK, Hong EG, Choi CS, Kim HK, Kim DM, Yoo JM, Ihm SH, Choi MG, Yoo HJ, Park SW, Larsen PR
- KMID: 2200383
- J Korean Soc Endocrinol.
- 2003 Aug;18(4):379-391.
BACKGROUND: The regulation of gene transcription can be controlled by both positive (enhancer) and negative (silencer) regulatory sequences. Several enhancer and silencer elements have been described in the 5' region... -
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- Thyroid Hormone Receptor Dynamics in Thyroid Hormone Response Elements of the Human Type 1 Iodothyronine Deiodinase Gene
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Lee SJ, Park CY, Jeong IK, Hong EG, Choi CS, Kim HK, Kim DM, Yoo JM, Ihm SH, Choi MG, Yoo HJ, Park SW, Larsen PR
- KMID: 2200307
- J Korean Soc Endocrinol.
- 2003 Jun;18(3):283-295.
BACKGROUND: Type 1 iodothyronine deiodinase (D1), the product of the hdio1 gene, is involved in thyroid hormone activation by the deiodination of thyroxine (T4) to form 3, 5, 3'-triiodothyronine (T3).... -
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- Responsive site on the thrombospondin-1 promotor to down-regulation by phorbol 12-myristate 13-acetate in porcine aortic endothelial cells
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Kim SA, Hong KJ
- KMID: 755077
- Exp Mol Med.
- 2000 Sep;32(3):135-140.
Thrombospondin-1 (TSP-1), a multifunctional extracellular matrix protein, inhibits neovascularization and is implicated in the regression of tumor growth and metastasis. We found that the synthesis of TSP-1 in... -
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- Analysis of Glucocorticoid Response Element and TPA Response Element of Rat Thyrotropin-Releasing Hormine Gene by Site-Directed Mutagenesis
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Kim SW, Kim JW, Kim YS, Choi YK, Yang IM, Woo JT, Chung WW
- KMID: 2199458
- J Korean Soc Endocrinol.
- 1999 Jun;14(2):278-292.
BACKGROUND: We previously demonstrated that a GRE/TRE composite sequence, which is located between 200 bp and 220 bp relative to the transcriptional start site of rat TRH gene, is responsible... -
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- Chronic Antidepressant Administration Increases the Expression of PhosphoCREB(Phosphorylated Cyclic AMP Response Element Binding Protein) in Rat Hippocampus
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Kim SY, Han JH, Lee CU, Paik IH
- KMID: 2340212
- J Korean Neuropsychiatr Assoc.
- 1998 Sep;37(5):992-998.
OBJECTIVES: This study designed to assess the expression of phosphoCREB in rat hippocampus after chronic administration of various antidepressants in comparison with chronic administration of antipsychotic and antianxiety drugs. METHODS: Male... -
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- Identification of TPA - Response Element (TRE) in the Rat Thyrotropin - Releasing Hormone (TRH) Gene
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Jung WW, Choi YK, Yang IM, Seo KS, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK, Park SJ
- KMID: 2461565
- J Korean Soc Endocrinol.
- 1994 Sep;10(3):200-213.
There are two potential imperfect copies of the TRE consensus sequence between -47 and -113bp position on 5' upstream of the rat TRH gene. The upstream element(5'-TGcCgTCA-3') is located between... -
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- Characterization of Cyclic AMP Response Element (CRE) in the Promoter of the Rat Thyrotropin Releasing Hormone (TRH) Gene
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Jung WW, Yang IM, Seo KS, Jung SW
- KMID: 2461510
- J Korean Soc Endocrinol.
- 1994 Sep;9(3):190-199.
We investigated whether the two variant elements of CRE(TGcCGTCA[5'CRE], TGACcTCA[3'CRE]) in the 5'flanking region of the rat TRH gene, which are different from the CRE consensus sequence(5'-TGACGTCA-3') by one base... -
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