- Growth and Invasion of Sporadic Colorectal Adenocarcinomas in Terms of Genetic Change
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Roh SA, Choi EY, Cho DH, Jang SJ, Kim SY, Kim YS, Kim JC
- KMID: 1778028
- J Korean Med Sci.
- 2010 Mar;25(3):353-360.
- doi: 10.3346/jkms.2010.25.3.353
Integrative genetic changes were examined in relation to tumor growth and progression of sporadic colorectal cancers. Ninety-two sporadic colorectal cancer patients and 12 human colorectal cancer cell lines were evaluated.... -
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- Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia
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Kim J, Lyu CJ, Shin S, Lee ST, Choi JR
- KMID: 2373579
- Ann Lab Med.
- 2016 Sep;36(5):475-480.
- doi: 10.3343/alm.2016.36.5.475
BACKGROUND: Intrachromosomal amplification of chromosome 21 (iAMP21) is known to be associated with poor prognosis in B-cell ALL (B-ALL). To determine the frequency and clinical characteristics of iAMP21 in Korean... -
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- Diagnostic Utility of Multiprobe Fluorescence in situ Hybridization Assay for Detecting Cytogenetic Aberrations in Acute Leukemia
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Kim BR, Choi JL, Kim JE, Woo KS, Kim KH, Kim JM, Kim SH, Han JY
- KMID: 1791920
- Ann Lab Med.
- 2014 May;34(3):198-202.
- doi: 10.3343/alm.2014.34.3.198
BACKGROUND: Specific cytogenetic aberrations detected by conventional karyotyping or FISH play a major role in the diagnosis, prognosis, and treatment of patients with acute leukemia. The FISH technique enhances the... -
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- Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
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Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH
- KMID: 1009391
- Exp Mol Med.
- 2009 Oct;41(10):695-706.
- doi: 10.3858/emm.2009.41.10.076
Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and... -
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- Akt is involved in the inhibition of cell proliferation by EGF
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Jeon SH, Jeong WJ, Cho JY, Lee KH, Choi KY
- KMID: 756072
- Exp Mol Med.
- 2007 Aug;39(4):491-498.
Axin is a negative regulator of the Wnt/beta-catenin pathway and is involved in the regulation of axis formation and proliferation. Involvement of Axin in the regulation of other signaling pathways... -
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- Transcriptional repression of type I procollagen genes during adipocyte differentiation
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Yi TG, Choi HM, Park RW, Sohn KY, Kim IS
- KMID: 1457541
- Exp Mol Med.
- 2001 Dec;33(4):269-275.
Adipocyte differentiation is a very complex process in which whole-cell changes are accompanied. Among them, type I procollagen gene has been shown to specifically decrease during adipocyte differentiation; however, little... -
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- Helicobacter pylori Urease Activity is Influenced by Ferric Uptake Regulator
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Lee JS, Choe YH, Lee JH, Lee HJ, Lee JH, Choi YO
- KMID: 1779604
- Yonsei Med J.
- 2010 Jan;51(1):39-44.
- doi: 10.3349/ymj.2010.51.1.39
PURPOSE: The role of the Ferric Uptake Regulator (FUR) in the acid resistance of Helicobacter pylori (H. pylori) has been thought to be independent of urease. However, we demonstrated in... -
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- Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury
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Lee MJ, Kwak YK, You KR, Lee BH, Kim DG
- KMID: 1088599
- Exp Mol Med.
- 2009 Apr;41(4):243-252.
- doi: 10.3858/emm.2009.41.4.027
Oxidative stress is critical for causing cardiac injuries during ischemia-reperfusion (IR), yet the molecular mechanism for this remains unclear. In the present study, we observe that hypoxia and reoxygenation, a... -
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- Characterization of Immortalized Human Corneal Endothelial Cell Line using HPV 16 E6/E7 on Lyophilized Human Amniotic Membrane
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Kim HJ, Ryu YH, Ahn JI, Park JK, Kim JC
- KMID: 1099072
- Korean J Ophthalmol.
- 2006 Mar;20(1):47-54.
- doi: 10.3341/kjo.2006.20.1.47
PURPOSE: To establish the immortalized human corneal endothelial cell line (IHCEn) by transducing human papilloma virus (HPV) 16 E6/E7 oncogenes, and to identify their characteristics when cultivated on a... -
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