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The optimal model of reperfusion injury in vitro using H9c2 transformed cardiac myoblasts

Son E, Lee D, Woo CW, Kim YH

An in vitro model for ischemia/reperfusion injury has not been well-established. We hypothesized that this failure may be caused by serum deprivation, the use of glutamine-containing media, and absence of...
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Initial Experience of ACE68 Reperfusion Catheter in Patients with Acute Ischemic Stroke Related to Internal Carotid Artery Occlusion

Jang HG, Park JS, Lee JM, Kwak HS

OBJECTIVE: Penumbra ACE68 reperfusion catheter is a new large bore aspiration catheter used for reperfusion of large vessel occlusion. The objective of this study was to investigate the efficacy of...
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Hyperintense Acute Reperfusion Marker after Intravenous Thrombolysisin a Patient with Hyperacute Ischemic Stroke

Kang J, Kim CH, Choi NC, Kim SK

No abstract available.
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Characteristic Signs on T2*-Based Imaging and Their Relationship with Results of Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Evidence to Date

Ko HC, Ryu CW, Yun SJ, Koh JS, Shin HS, Kim EJ

PURPOSE: Characteristic signs – the susceptibility vessel sign (SVS) and the prominent hypointense vessel sign (PHVS) – on T2*-based magnetic resonance imaging (T2*MRI) can be seen for acute ischemic stroke...
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Dual Effect of Hepatic Macrophages on Liver Ischemia and Reperfusion Injury during Liver Transplantation

Lu TF, Yang TH, Zhong CP, Shen C, Lin WW, Gu GX, Xia Q, Xu N

Ischemia-reperfusion injury (IRI) is a major complication in liver transplantation (LT) and it is closely related to the recovery of grafts' function. Researches has verified that both innate and adaptive...
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Neuroprotectants in the Era of Reperfusion Therapy

Chamorro A

For decades, numerous pharmacological and non-pharmacological strategies have been evaluated without success to limit the consequences of the ischemic cascade, but more rarely the therapies were explored as add on...
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Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation

Kim J

Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative and nitrative stresses; however, an effective approach to limit IRI remains...
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Blood Pressure May Be Associated with Arterial Collateralization in Anterior Circulation Ischemic Stroke before Acute Reperfusion Therapy

Jiang B, Churilov L, Kanesan L, Dowling R, Mitchell P, Dong Q, Davis S, Yan B

BACKGROUND AND PURPOSE: Leptomeningeal collaterals maintain arterial perfusion in acute arterial occlusion but may fluctuate subject to arterial blood pressure (ABP). We aim to investigate the relationship between ABP and...
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Lower limb compartment syndrome by reperfusion injury after treatment of arterial thrombosis post-laparoscopic radical hysterectomy and pelvic lymph node dissection for cervical cancer

Yeon J, Jung YW, Yang SS, Kang BH, Lee M, Ko YB, Yang JB, Lee KH, Yoo HJ

Compartment syndrome is a clinical condition associated with decreased blood circulation that can lead to swelling of tissue in limited space. Several factors including lithotomy position, prolonged surgery, intermittent pneumatic...
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Computed Tomography-Based Thrombus Imaging for the Prediction of Recanalization after Reperfusion Therapy in Stroke

Heo JH, Kim K, Yoo J, Kim YD, Nam HS, Kim EY

The prediction of successful recanalization following thrombolytic or endovascular treatment may be helpful to determine the strategy of recanalization treatment in acute stroke. Thrombus can be detected using noncontrast computed...
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Concise Bedside Surgical Management of Profound Reperfusion Injury after Vascular Reconstruction in Severe Trauma Patient: Case Report

Chung HJ, Kim SY, Byun CS, Kwon KY, Jung PY

For an orthopaedic surgeon, the critical decisions to either amputate or salvage a limb with severe crushing injury with progressive ischemic change due to arterial rupture or occlusion can become...
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Standardized surgical techniques for adult living donor liver transplantation using a modified right lobe graft: a video presentation from bench to reperfusion

Hwang S, Ha TY, Ahn CS, Moon DB, Kim KH, Song GW, Jung DH, Park GC, Lee SG

After having experienced more than 2,000 cases of adult living donor liver transplantation (LDLT), we established the concepts of right liver graft standardization. Right liver graft standardization intends to provide...
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The Effect of Ischemic Preconditioning on the Expression of Serum Cytokines after 2 Hours Ischemia and Timely Reperfusion in the Hindlimb of Mice

Jin JH, Kim SJ, Seo Y, Kim S

The large volume of reactive oxygen species are generated during reperfusion after transient or post-procedural ischemia, which leads to cell injury. This ischemia-reperfusion (IR) injury may cause local and even...
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The Changes of Pro-inflammatory Cytokines in Serum according to the Reperfusion Time after Ischemia of Left Common Iliac Artery in Mice

Park KS, Kim SJ, Seo Y

Ischemia-reperfusion injury arises from the restoration of blood supply after ischemia. Both reactive oxygen species and various cytokines produced by activated immune cells are the primary causal risk factors for...
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Arrhythmogenic potential develops rapidly at graft reperfusion before the start of hypotension during living-donor liver transplantation

Lee HM, Park SK, Moon YJ, Kim JW, Kim SK, Sang BH, Seo DK, Yoo BW, Hwang GS

BACKGROUND: Detailed profiles of acute hypothermia and electrocardiographic (ECG) manifestations of arrhythmogenicity were examined to analyze acute hypothermia and ventricular arrhythmogenic potential immediately after portal vein unclamping (PVU) in living-donor...
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Neuroprotective Effect of Resveratrol on Acute Brain Ischemia Reperfusion Injury by Measuring Annexin V, p53, Bcl-2 Levels in Rats

Kizmazoglu C, Aydin HE, Sevin IE, Kalemci O, Yuceer N, Atasoy MA

BACKGROUND: Cerebral ischemia is as a result of insufficient cerebral blood flow for cerebral metabolic functions. Resveratrol is a natural phytoalexin that can be extracted from grape's skin and had...
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Initial Experience Using the 5MAX(TM) ACE Reperfusion Catheter in Intra-arterial Therapy for Acute Ischemic Stroke

John S, Hussain MS, Toth G, Bain M, Uchino K, Hui FK

OBJECTIVES: The 5MAX ACE is a new large bore aspiration catheter available for vessel recanalization for treatment of acute ischemic stroke (AIS). We report our initial experience with its use. METHODS:...
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Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity

Xia A, Xue Z, Wang W, Zhang T, Wei T, Sha X, Ding Y, Zhou W

To investigate the alteration of c-Jun N-terminal kinase (JNK) activity after myocardial ischemia reperfusion injury (MIRI) and further explore the effect of naloxone postconditioning on MIRI. Forty male Sprague Dawley...
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Experimental Study on the Effect of Intravenous Stem Cell Therapy on Intestinal Ischemia Reperfusion Induced Myocardial Injury

Zickri MB, Embaby A, Metwally H

  • KMID: 2054552
  • Int J Stem Cells.
  • 2013 Nov;6(2):121-128.
BACKGROUND AND OBJECTIVES: The myocyte death that follows intestinal ischemia reperfusion (I/R) injury is a major factor contributing to high mortality and morbidity in ischemic heart disease. The purpose of...
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The Role of HMGB1 and the Effect of Ethyl Pyruvate on Ischemia and Reperfusion Injury of Rat Kidney

Chung KY, Park JJ, Kim YS

  • KMID: 2201877
  • J Korean Soc Transplant.
  • 2007 Dec;21(2):234-240.
PURPOSE: High mobility group box-1 (HMGB1) was identified as a DNA binding protein that functions as a co-factor for proper transcriptional regulation in somatic cells. Extra- cellular HMGB1 acts as...
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